Prevalence of adulteration in dietary supplements and recommendations for safe supplement practices in sport [PDF]
Front Sports Act Living, 2023 The prevalence of dietary supplement use among athletes continues to rise with 60–80% of athletes often reporting current or previous use of dietary supplements.
Andrew J. Galpin +6 more
core +3 more sources
Computational metabolomics reveals overlooked chemodiversity of alkaloid scaffolds in Piper fimbriulatum [PDF]
The Plant Journal, Volume 121, Issue 5, March 2025.SUMMARY Plant specialized metabolites play key roles in diverse physiological processes and ecological interactions. Identifying structurally novel metabolites, as well as discovering known compounds in new species, is often crucial for answering broader biological questions.
Tito Damiani +8 more
wiley +2 more sources
Annual Banned‐Substance Review 17th Edition—Analytical Approaches in Human Sports Drug Testing 2023/2024 [PDF]
Drug Testing and Analysis, Volume 17, Issue 8, Page 1417-1442, August 2025.Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario Thevis +2 more
wiley +2 more sources
Matrix Metalloproteinases on Skin Photoaging [PDF]
Journal of Cosmetic Dermatology, Volume 23, Issue 12, Page 3847-3862, December 2024.ABSTRACT Background Skin aging is characterized by an imbalance between the generation and degradation of extracellular matrix molecules (ECM). Matrix metalloproteinases (MMPs) are the primary enzymes responsible for ECM breakdown. Intrinsic and extrinsic stimuli can induce different MMPs.
Chao Feng +4 more
wiley +2 more sources
YS-49 activates the PI3K/AKT signaling pathway in MC3T3-E1 cells to enhance osteoblast differentiation and inhibits glucocorticoid-induced bone loss in vivo [PDF]
BMC Musculoskeletal DisordersBackground Glucocorticoid-induced osteoporosis (GIOP) is a bone disorder marked by decreased bone density and an elevated risk of fracture. The Phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT) signaling pathway plays a pivotal role in regulating ...
Yuting Cao +6 more
doaj +2 more sources
Use of liquid chromatography‐tandem mass spectrometry for determination of higenamine in urine following oral administration of traditional Chinese medicine [PDF]
Drug Test Anal, 2022 Chengjun Guo +5 more
openalex +2 more sources
Frontiers in Pharmacology, 2021 Oxidative stress damage is known as one of the important factors that induce neuropathic pain (NP). Using antioxidant therapy usually achieves an obvious curative effect and alleviates NP. Previous pharmacological studies have shown that higenamine (Hig)
Bing Yang +7 more
doaj +1 more source
Annual banned-substance review: Analytical approaches in human sports drug testing 2019/2020. [PDF]
, 2021 Analytical chemistry-based research in sports drug testing has been a dynamic endeavor for several decades, with technology-driven innovations continuously contributing to significant improvements in various regards including analytical sensitivity ...
Geyer, H., Kuuranne, T., Thevis, M.
core +5 more sources
Identification of key bioactive anti-migraine constituents of Asari radix et rhizoma using network pharmacology and nitroglycerin-induced migraine rat model [PDF]
, 2022 Purpose: To elucidate the bioactive constituents of Asari radix et rhizoma (ARR) in treating migraine based on network pharmacology and nitroglycerin-induced migraine rat model.
Dai, Zhong-Hua +5 more
core +2 more sources
Drug Testing and Analysis, Volume 15, Issue 11-12, Page 1488-1502, November-December 2023., 2023 Patterns of higenamine‐ and benzylisoquinoline alkaloid‐derived urinary metabolites were investigated concerning their utility in supporting case management in sports drug testing, with phase‐II metabolites of reticuline and isococlaurine showing great potential.
Ana Rubio +14 more
wiley +1 more source