Results 61 to 70 of about 1,066 (203)
The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou +11 more
wiley +1 more source
Variation of Secondary Metabolites in the Aerial Biomass of
Cryptocarya alba is an important tree species in the Chilean sclerophyllous forest. Its leaves and bark are used in traditional medicine to treat liver diseases and rheumatism.
Ady Giordano +11 more
doaj +1 more source
A Review of the Secondary Metabolites and Biological Activities of Tinospora crispa (Menispermaceae) [PDF]
Tinospora crispa Beumee, a herbaceous climber, has been widely used in traditional medicine for treating various ailments such as contusion, septicaemia, fever, fracture, scabies and other tropical ulcers.
Koay, F, Koay, YC
core +2 more sources
Progress on the development of Class A GPCR‐biased ligands
Class A G protein‐coupled receptors (GPCRs) continue to garner interest for their essential roles in cell signalling and their importance as drug targets. Although numerous drugs in the clinic target these receptors, over 60% GPCRs remain unexploited. Moreover, the adverse effects triggered by the available unbiased GPCR modulators, limit their use and
Paula Morales +20 more
wiley +1 more source
Phytochemical, Toxicological and Pharmacological Studies of Asiasari Radix et Rhizoma: A Review [PDF]
Herba Asari and Asiasari Radix (AR) have a centuries-old history as a folk medicine in China, Korea and Japan. AR has long been used in combination with other herbs to treat cough, toothache, headache, neuralgia, aphthous stomatitis, gingivitis, chronic ...
Kim, S-J, Ramalingam, M
core +2 more sources
Plant‐Derived Treatments for Different Types of Muscle Atrophy
Potential mechanisms of phytoactive compounds in the treatment of muscle atrophy. ABSTRACT With the development of medicine and chemistry, an increasing number of plant‐derived medicines have been shown to exert beneficial therapeutic on the treatment of various physical and psychological diseases. In particular, by using physical chemistry methods, we
Xingpeng Wang +9 more
wiley +1 more source
Fruits of Nandina domestica are (Sometimes) Cyanogenic and (Sometimes) Hazardous to Birds [PDF]
A 12-month survey of cyanogenesis in the fruits and leaves of Nandina domestica (Berberidaceae) revealed that the leaves are strongly cyanogenic throughout the year, as measured by the Feigl-Anger test. Fruits vary in their cyanogenic potential depending
Zona, Scott
core +1 more source
ABSTRACT One main cause of persistent back discomfort is intervertebral disc degeneration (IDD), with inflammation and extracellular matrix (ECM) degradation playing critical roles. This study investigates the role of ZIP8, a zinc transporter, in IDD pathogenesis, focusing on its effects on inflammatory responses, ECM degradation and Wnt/β‐catenin ...
Jun Xu +9 more
wiley +1 more source
Enantiomeric determination of drugs in pharmaceutical formulations and biological samples by Electrokinetic Chromatography [PDF]
Chirality is a relevant issue in the pharmaceutical field due to the different biological activity that enantiomers of a chiral drug can show. In fact, the desired biological or pharmaceutical activity might be present in only one of the enantiomers ...
Casado Navas, Natalia +3 more
core +1 more source

