Results 101 to 110 of about 4,092,880 (310)

Dual Query: Practical Private Query Release for High Dimensional Data

open access: yesThe Journal of Privacy and Confidentiality, 2017
We present a practical, differentially private algorithm for answering a large number of queries on high dimensional datasets. Like all algorithms for this task, ours necessarily has worst-case complexity exponential in the dimension of the data. However,
Marco Gaboardi   +4 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Regularized and robust regression methods for high dimensional data [PDF]

open access: yes, 2014
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University London.Recently, variable selection in high-dimensional data has attracted much research interest.
Hashem, Hussein Abdulahman
core  

Replication Data for: Stiefel-Whitney topological charges in a three-dimensional acoustic nodal-line crystal

open access: yes, 2023
Experimental data for the paper "Stiefel-Whitney topological charges in a three-dimensional acoustic nodal-line crystal"
Xue, Haoran, Zhang, Baile
core   +1 more source

Guided quantum compression for high dimensional data classification

open access: yesMachine Learning: Science and Technology
Quantum machine learning provides a fundamentally different approach to analyzing data. However, many interesting datasets are too complex for currently available quantum computers.
Vasilis Belis   +5 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Visualization for high-dimensional data: VisHD

open access: yes, 2011
[[abstract]]This paper presents a visualization tool, VisHD, that can visualize the spatial distribution of vector points in high dimensional feature space. It is important to handle high dimensional information in many areas of computer science.
Chiang, Cheng-Chieh   +3 more
core  

High-dimensional Structured Additive Regression Models: Bayesian Regularisation, Smoothing and Predictive Performance [PDF]

open access: yes, 2009
Data structures in modern applications frequently combine the necessity of flexible regression techniques such as nonlinear and spatial effects with high-dimensional covariate vectors. While estimation of the former is typically achieved by supplementing
Konrath, Susanne   +2 more
core   +1 more source

SLSB-forest:approximate k nearest neighbors searching on high dimensional data

open access: yesDianxin kexue, 2017
The study of approximate k nearest neighbors query has attracted broad attention.Local sensitive hash is one of the mainstream ways to solve this problem.Local sensitive hash and its varients have noted the following problems:the uneven distribution of ...
Tu QIAN   +3 more
doaj   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

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