Multi-Platform Multivariate Regression with Group Sparsity for High-Dimensional Data Integration. [PDF]
Qin S, Zhang G, Gao X, Wu Y.
europepmc +1 more source
Identification of prognostic and predictive biomarkers in high-dimensional data with PPLasso. [PDF]
Zhu W, Lévy-Leduc C, Ternès N.
europepmc +1 more source
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Uniform in Bandwidth Consistency of the <i>L</i><sup>1</sup>-Modal Regression Estimator for High-Dimensional Data. [PDF]
Almulhim FA, Alamari MB, Laksaci A.
europepmc +1 more source
Knockoff procedure for false discovery rate control in high-dimensional data streams. [PDF]
Wai Tsang K, Tsung F, Xu Z.
europepmc +1 more source
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
Ensemble learning for predicting birth trauma using high-dimensional data in the neonatal intensive care unit. [PDF]
Odhiambo CO +3 more
europepmc +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Deep autoencoder for low dimensionality for high dimensional data in regression models and direct inverse analysis of models. [PDF]
Kaneko H.
europepmc +1 more source
An Ensemble Outlier Detection Method Based on Information Entropy-Weighted Subspaces for High-Dimensional Data. [PDF]
Li Z, Zhang L.
europepmc +1 more source

