NanomaterialsHigh-entropy ceramics have gained wider attention due to their structural integrity and stability, which can be used in various functional applications.
Mariappan Anandkumar +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Synthetic Strategies toward High Entropy Materials: Atoms-to-Lattices for Maximum Disorder. [PDF]
Cryst Growth Des, 2023 Buckingham MA, Skelton JM, Lewis DJ.
europepmc +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
High-entropy alloys as magnetic shielding materials in low-frequency wireless power transmission
Materials Today AdvancesSoft magnetic materials are required to exhibit high saturation magnetization and low coercivity. Iron-based metal alloys, such as FeMnZn, are commonly used commercial soft magnetic materials with electromagnetic shielding functions.
Cheng-Hsien Yeh +6 more
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High-Entropy Materials in SOFC Technology: Theoretical Foundations for Their Creation, Features of Synthesis, and Recent Achievements. [PDF]
Materials (Basel), 2022 Pikalova EY +3 more
europepmc +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Randomly adjustable stacked open thin-shell cells mechanical metamaterials
Theoretical and Applied Mechanics LettersOpen thin-shell structures exhibit advantages such as lightweight properties and high energy absorption efficiency. By randomly stacking these structures as unit cells, adjustable mechanical metamaterials with tunable and stable mechanical properties can
Xiaolin Guo, Bohua Sun
doaj +1 more source
High-entropy materials for catalysis: A new frontier. [PDF]
Sci Adv, 2021 Sun Y, Dai S.
europepmc +1 more source