Results 141 to 150 of about 18,114,009 (290)

Aerosol Delivery Efficiency With High-Flow Nasal Cannula Therapy in Neonatal, Pediatric, and Adult Nasal Upper-Airway and Lung Models

Respiratory care
BACKGROUND: High-flow nasal cannula (HFNC) systems employ different methods to provide aerosol to patients. This study compared delivery efficiency, particle size, and regional deposition of aerosolized bronchodilators during HFNC in neonatal, pediatric,
Robert M. DiBlasi, Rebecca J. Engberg, J. Poli, Kristen E. Carlin, N. Kontoudios, P. Longest, Masaki Kajimoto   +6 more
semanticscholar   +1 more source

Exhaled air dispersion during high-flow nasal cannula therapy versus CPAP via different masks

European Respiratory Journal, 2019
Background High-flow nasal cannula (HFNC) is an emerging therapy for respiratory failure but the extent of exhaled air dispersion during treatment is unknown.
David S. C. Hui, Benny K. Chow, Thomas S F Lo, O. Tsang, Fanny W. S. Ko, S. Ng, T. Gin, M. Chan   +7 more
semanticscholar   +1 more source

Channelrhodopsin ion selectivity determines mechanisms and efficacy of optogenetic defibrillation in human atria and ventricles

The Journal of Physiology, EarlyView.
Abstract figure legend A, we used in silico models of human cardiomyocytes and microelectrode recordings on transgenic zebrafish hearts to study electrophysiology during optogenetic perturbations. Specifically, we compared effects of three distinct classes of channelrhodopsins: the cation non‐selective Chlamydomonas reinhardtii channelrhodopsin‐2 (ChR2)
Sophia Ohnemus, Albert Dasí, Ahmed F. Ramadan, Joachim Greiner, Eike M. Wülfers, Matthew R. Stoyek, Linda Tillert, Johannes Vierock, T. Alexander Quinn, Peter Kohl, Patrick M. Boyle, Viviane Timmermann, Franziska Schneider‐Warme   +12 more
wiley   +1 more source

Respiratory Support With Nasal High Flow Reduces Opioid Requirements During Endoscopic Retrograde Cholangiopancreatography

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Nasal high flow (NHF) improves oxygenation, reduces the work of breathing, and stabilizes ventilation. In endoscopic retrograde cholangiopancreatography (ERCP) under dexmedetomidine‐based sedation, opioids are often required but increase the risk of respiratory depression and delayed recovery.
Tomotaka Mori, Takao Ayuse, Shuntaro Sato, Taiga Ichinomiya, Rintaro Yano, Akane Shimakura, Yasuhiko Nakao, Kosuke Takahashi, Masanori Fukushima, Masafumi Haraguchi, Ryu Sasaki, Eisuke Ozawa, Satoshi Miuma, Stanislav Tatkov, Tetsuya Hara, Hisamitsu Miyaaki   +15 more
wiley   +1 more source

Transition to Weight-Based High-Flow Nasal Cannula Use Outside of the ICU for Bronchiolitis

JAMA Network Open
This cohort study assesses changes in intensive care unit (ICU) admission rate, hospital length of stay, and use of noninvasive and invasive ventilation after the adoption of weight-based high-flow nasal cannula protocol in hospitalized patients aged 0 ...
Robert J. Willer, Patrick W. Brady, A. Tyler, Jennifer D. Treasure, Eric R. Coon   +4 more
semanticscholar   +1 more source

High-Flow Nasal Cannula Compared With Conventional Oxygen Therapy or Noninvasive Ventilation Immediately Postextubation

, 2020
International audienceObjectives: Reintubation after failed extubation is associated with increased mortality and longer hospital length of stay. Noninvasive oxygenation modalities may prevent reintubation.
Trivedi, Vatsal, Wang D., Goligher, Ewan C, Chaudhuri D., Burns, Karen E A, Jaber, Samir, Salvatore M. Maggiore, Mancebo, Jordi, Maggiore S. M., Maggiore, Salvatore M, Jordi Mancebo, Frat, Jean Pierre, Hodgson, Carol L, Granton D., Sameer Jog, Ewan C. Goligher, Granton, David, Dipayan Chaudhuri, Burns, Karen, Brochard L., Carol L. Hodgson, Burns, Karen E.A., Tommaso Mauri, Gonzalo Hernandez, Rochwerg, Bram, Karen E. A. Burns, Maggiore, Salvatore M., Helviz Y., Ricard, Jean Damien, Sharon Einav, Wang, Dominic, Hodgson, Carol, Samir Jaber, Bram Rochwerg, Helviz, Yigal, Trivedi V., Goligher, Ewan, Hernandez G., Ricard, Jean-Damien, Jean-Pierre Frat, Einav, Sharon, Laurent Brochard, Frat, Jean-Pierre, Jaber S., Mauri T., Hernandez, Gonzalo, Vatsal Trivedi, Brochard, Laurent, Hodgson, Carol L., Jean-Damien Ricard, Goligher, Ewan C., Mauri, Tommaso, Jog, Sameer, Jog S., Ricard J. D., Burns K. E. A., Hodgson C. L., Frat J. P., Goligher E. C., Rochwerg B., Maggiore, Salvatore, Dominic Wang, Yigal Helviz, Chaudhuri, Dipayan, David Granton, Mancebo J., Einav S.   +66 more
core   +1 more source

Calibration‐Free Estimation of Cerebrovascular Reactivity From Resting‐State BOLD fMRI Using Reconstructed Respiratory Fluctuations

Magnetic Resonance in Medicine, Volume 96, Issue 6, Page 2755-2766, December 2026.
ABSTRACT Purpose Cerebrovascular reactivity (CVR) provides an important index of vascular health and is conventionally quantified using a hypercapnic gas or breath‐hold challenge in conjunction with blood‐oxygen‐level‐dependent functional magnetic resonance imaging (BOLD‐fMRI).
Abdoljalil Addeh, Ethan Church, Muhammad Mahajna, Karen Ardila, Pattarawut Charatpangoon, Alexander D. Cohen, Yang Wang, Rebecca J. Williams, G. Bruce Pike, M. Ethan MacDonald   +9 more
wiley   +1 more source

Predictive Factors for Failure of High-Flow Nasal Cannula Therapy in Pediatric Intensive Care Unit [PDF]

Objective: High-flow nasal cannula (HFNC) therapy is widely used to manage respiratory distress in children. However, treatment failure requiring advanced respiratory support is associated with increased rates of morbidity and mortality.
Rana İşgüder, Derşan Onur, Gülhan Atakul   +2 more
core   +1 more source

Hemophagocytic Lymphohistiocytosis in a Patient With Alcohol‐Associated Liver Disease: A Case Report Highlighting Diagnostic Challenges

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Hemophagocytic lymphohistiocytosis (HLH) is a life‐threatening hyperinflammatory syndrome with nonspecific clinical manifestations that can mimic common conditions in patients with alcohol dependence. Early clinical suspicion and rapid initiation of treatment are essential to prevent fatal outcomes.
Adalis Rivera, Hakan R. Toka, Yasser Samra, Aleena Khan, Kathryn Bower   +4 more
wiley   +1 more source

The Role of Heated Humidified High-flow Nasal Cannula as Noninvasive Respiratory Support in Neonates

, 2017
Recently, heated humidified high-flow nasal cannula (HHHFNC) has been introduced and applied as a noninvasive respiratory support in neonates. Although HHHFNC is widely used in neonates presenting with respiratory distress, the efficiency and safety when
Li-Yi Tsai, Yi-Ling Chen, Yu-Hsuan Chien, Shu-Chi Mu, Ke-Yun Chao   +4 more
core   +1 more source