Results 81 to 90 of about 20,605,475 (335)

High frame rate ultrasound imaging of human carotid artery dynamics

open access: yes, 2012
The carotid artery (CA) is one of the main arteries of interest to cardiovascular research, because of the clinical relevance of CA plaques as culprits of stroke and the accessibility of the CA for cardiovascular health screening. Viscoelastic properties
Nico de Jong   +9 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

A Review of Ultrasound Imaging Methods and Techniques to Enhance Their Frame Rate [PDF]

open access: yesIranian Journal of Electrical and Electronic Engineering
Increasing the frame rate of ultrasound imaging while keeping image quality is important for following fast movements, especially the heart. There are different modalities for B-mode image recording, including line-by-line scanning with linear, phased ...
Seyyedeh Ensiyeh Hashemi, Hamid Behnam
doaj  

P85 HIGH FRAME RATE DYNAMIC DISPLAY ULTRASOUND VECTOR FLOW IMAGING FOR QUANTITATIVE STUDIES OF HEMODYNAMICS OF CAROTID ARTERIES

open access: yesArtery Research, 2017
Advanced atherosclerotic patients are faced with significant risks of stroke, which are very likely to cause death or irreversible physical disability. However, the growth of artery stenosis usually needs a very long development.
Yigang Du   +4 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

High Frame Rate X-Ray imaging with a 256x256 Pixel Single Photon Counting medipix2 detector

open access: yes, 2005
We report on high frame rate X-ray imaging tests with the Medipix2 single photon counting detector (single frames contain 256times256 pixel, 55 mum pitch, 13 bit counter) bump-bonded to a 300 mum thick silicon pixel detector.
A. SEBASTIANO   +3 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Plane-projection multi-photon microscopy for high-frame-rate Live Tissue Imaging [PDF]

open access: yes, 2011
We present a wide-field multi-photon microscopy that provides optical sectioning at high frame rate under biocompatible laser dosage.
Kuo, Chun-Hung   +7 more
core   +1 more source

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