Results 61 to 70 of about 710,614 (300)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Cosmic Reionization and the 21-cm signal: Comparison between an analytical model and a simulation [PDF]
, 2008 We measure several properties of the reionization process and the corresponding low-frequency 21-cm signal associated with the neutral hydrogen distribution, using a large volume, high resolution simulation of cosmic reionization.
Aghanim N. +6 more
core +3 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Effect of Radio Frequency Combined with Hot Air Heating on Degradation of Aflatoxin B1 and Corn Quality [PDF]
Shipin KexueThis study analyzed the effects of radio frequency-hot air treatment under different conditions of initial corn moisture content (19.05%, 22.25%, and 25.55%), radio frequency heating temperature (55, 65, 75, and 85 ℃) and heating time (10, 15, 20, and 25
ZHANG Jinfang, LI Mei, CHEN Wei
doaj +1 more source
Single phase matrix converter for radio frequency induction heating [PDF]
, 2006 Conventional converters for radio frequency induction heating usually follow an AC-DC-AC structure, which can exhibit non-unity power factor and introduce large harmonic currents into the utility supply.
Bingham, Chris +3 more
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
, 2011 The frequency of heating events in the corona is an important constraint on the coronal heating mechanisms. Observations indicate that the intensities and velocities measured in active region cores are effectively steady, suggesting that heating events ...
Amy R. Winebarger +41 more
core +1 more source
Heating of gas inside radio sources to mildly relativistic temperatures via induced Compton scattering [PDF]
, 2001 Measured values of the brightness temperature of low-frequency synchrotron radiation emitted by powerful extragalactic sources reach 10^11--10^12 K. If some amount of nonrelativistic ionized gas is present within such sources, it should be heated as a ...
A. Celotti +27 more
core +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source