Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley +1 more source
Abstract Central blood volume (CBV) reduction challenges circulatory and respiratory homeostasis, particularly during the initial compensatory phase (0–2 min), when rapid physiological adaptations occur. In this study, we examined dynamic cardiorespiratory responses to CBV reduction using lower‐body negative pressure (LBNP) in 11 healthy young males ...
Marina Feeley +7 more
wiley +1 more source
The effect of high frequency oscillatory ventilation combined with tracheal gas insufflation on extravascular lung water in patients with acute respiratory distress syndrome: a randomized, crossover, physiological study. [PDF]
Purpose: High frequency oscillation combined with tracheal gas insufflation (HFO-TGI) improves oxygenation in patients with Acute Respiratory Distress Syndrome (ARDS). There is limited physiologic data regarding the effects of HFO-TGI on hemodynamics and
Malachias, Sotirios +3 more
core
Abstract Dynamic resistance exercise (RE) produces sinusoidal fluctuations in blood pressure that are mirrored by middle cerebral artery blood velocity (MCAv). However, whether lower‐ or upper‐body RE elicits a differential cerebrovascular response has not yet been examined.
Stephanie Korad +2 more
wiley +1 more source
Myths and methodologies: Exposure and measurements under normobaric hypoxia
Abstract Usually, settings of normobaric hypoxia underestimate the environmental hypoxia they are supposed to reproduce. The likely steady state of water vapour pressure within the human airways keeps the partial pressure of inspired oxygen very close to the assumed value, but this does not apply to the calculation of environmental hypoxia or ...
Danilo Bondi
wiley +1 more source
Pediatric cardiac patients with pulmonary hemorrhage supported on ECMO: An ELSO registry study
Background: Pulmonary Hemorrhage (PH) is a rare but potentially devastating condition and pediatric cardiac patients are at increased risk for. ECMO may be used to safely support these patients, but data is limited.
Anton-Martin Pilar +3 more
doaj +1 more source
The efficacy of high frequency ventilation in severe neonatal respiratory failure [PDF]
Hægt er að lesa greinina í heild sinni með því að smella á hlekkinn View/OpenOBJECTIVE: To evaluate the efficacy of high frequency ventilation (HFV) in infants failing conventional ventilator therapy at our institution.
Atli Dagbjartsson +5 more
core
Cerebrovascular regulation during heat stress
Abstract Given that the brain is a highly metabolic organ and is enclosed by the skull, effective regulation of cerebral blood flow (CBF), not only for oxygen and nutrients supply but also as a means of convective heat exchange, is critical for preventing excessive elevations in brain temperature.
Kanoko Ito, Manabu Shibasaki
wiley +1 more source
The effect of budesonide delivered by high-frequency oscillatory ventilation on acute inflammatory response in severe lung injury in adult rabbits. [PDF]
Nemcova N +6 more
europepmc +1 more source
Brain strain: Blood flow and metabolism in environmental extremes
Abstract This narrative review compares and contrasts the most commonly encountered environmental stressors on human cerebrovascular functioning. From high altitude and space, extreme apnoea, heat and cold stress, the impact of these stressors on the regulation of cerebral blood flow (CBF) and oxygen metabolism (CMRO2${\mathrm{CM}}{{\mathrm{R}}_ ...
Dario Vrdoljak +3 more
wiley +1 more source

