Results 91 to 100 of about 148,673 (288)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Loss reduсing in pulse tranformer of betatron injection system [PDF]

open access: yes, 2017
Present betatrons have limited operating frequency, which is no more than 400 Hz. It's caused by thermal operating mode of betatron elements. High voltage injection system is the one of betatron elements. The highest thermal losses is observed in core of
Тойбаев, Н. Ж.   +1 more
core  

A novel miniature superconducting converter for 1 kA magnets [PDF]

open access: yes, 1996
A miniature full-wave converter to control the current of a superconducting magnet is developed and tested in our institutes. Typical design values of the device are: AC voltage of 35 V, current of 7 A, and frequency 50-60 Hz; DC voltage o f f 0.2 V, and
Fedorovsky, Michael A.   +3 more
core   +3 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Ferroresonant flux coupled battery charger [PDF]

open access: yes, 1987
A battery charger for incorporation into an electric-powered vehicle is disclosed. The charger includes a ferroresonant voltage-regulating circuit for providing an output voltage proportional to the frequency of an input AC voltage.
McLyman, Colonel W. T.
core   +1 more source

The UT 19-channel DC SQUID based neuromagnetometer [PDF]

open access: yes, 1991
A l9-channel DC SQUID based neuromagnetometer is under construction at the University of Twente (UT). Except for the cryostat all elements of the system are developed at the UT.
Ancum, G.K. van   +6 more
core   +4 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Novel vortex-transform for high frequency modulated patterns

open access: yesOptics Express, 2013
Se propone una nueva transformación de vórtice. Esta transformación permite generar funciones de valor complejo a partir de patrones de intensidad modulados, incluidos los componentes de alta frecuencia de la modulación, sin la generación de singularidades de fase inestables.
Daniel Sierra-Sosa   +3 more
openaire   +4 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

FREQUENCY DETERMINATION OF HIGH-FREQUENCY LINK FOR PERCPECTIVE ELECTRIC ROLLING STOCK

open access: yesNauka ta progres transportu, 2014
Purpose. Total mileage of Ukrainian electric railways is distributed approximately equally between the areas of direct and alternating current. A double system of electric rolling stock is used to pass jointing places of different current kinds without
D. O. Zabarylo
doaj   +1 more source

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