Results 111 to 120 of about 148,673 (288)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Design considerations, modelling, and control of dual-active full bridge for electric vehicles charging applications

open access: yesThe Journal of Engineering, 2019
The dual active full bridge (DAFB) is one of the promising isolated DC/DC converter topologies that will play a significant role in the future of electric vehicle (EV) integration in smart grids (SGs).
Fatma Jarraya   +5 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Solid state transformer technologies and applications: A bibliographical survey

open access: yesAIMS Energy, 2018
This paper presents a bibliographical survey of the work carried out to date on the solid state transformer (SST). The paper provides a list of references that cover most work related to this device and a short discussion about several aspects.
M. Ebrahim Adabi   +1 more
doaj   +1 more source

Signal path series step biased multidevice high efficiency amplifier Patent [PDF]

open access: yes, 1971
High efficiency transformerless amplitude modulator coupled to RF power ...
Kubicz, A. P.
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Analysis of Transformer Winding High Frequency Characteristics

open access: yesDEStech Transactions on Environment, Energy and Earth Science, 2016
As the terminal equipment in power system, power transformer is directly related to the safety and stability of power grid. The faults of transformer may bring great harms to the entire power grid and result in huge loss. The insulation defect of transformer winding is the main cause of the transformer fault. Therefore, the study of transformer winding
Fan Songhai, Zijian Wang, YuSheng Quan
openaire   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

4.5 kW High Frequency Transformer Design for Dual Active Bridge (DAB)

open access: yesJurnal Elkomika
ABSTRAK Indonesia bertujuan untuk beralih dari bahan bakar fosil ke sumber energi terbarukan, dengan target integrasi sebesar 23% pada tahun 2025 dan 31% pada tahun 2050.
NAUFAL HILMI FAUZAN   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy