Results 121 to 130 of about 148,673 (288)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Design of a high‐frequency transformer based on amorphous cut cores for insulation breakdown testing

open access: yesHigh Voltage
Innovative test methods are required to keep up with the increased demand for insulation materials which can withstand the high‐frequency square‐wave voltages generated by power‐electronic equipment.
Gijs Lagerweij   +1 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Design of a High Frequency Isolation Auxiliary Transformer for Urban Rail Vehicle

open access: yes机车电传动, 2017
This paper introduced the design ideas of a high frequency isolation auxiliary transformer, and demonstrated its key design for core, windings, parasitic inductance, loss and so on.
ZHOU Shuai   +4 more
doaj  

Development of high frequency low weight power magnetics for aerospace power systems [PDF]

open access: yes
A dominant design consideration in the development of space type power mangetic devices is the application of reliable thermal control methods to prevent device failure which is due to excessive temperature rises and hot temperatures in critical areas ...
Schwarze, G. E.
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Active Electrically Small Antenna Based on Superconducting Quantum Array

open access: yes, 2012
We introduce Superconductive Quantum Arrays (SQAs) and propose to use these structures as active Electrically Small Antennas (ESA). Several prototypes of the active ESA were fabricated using Nb process with critical current density 4.5 kA/cm2 and ...
Klenov, Nikolay V.   +4 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Design Considerations on Voltage and Current Transfer Ratio of High-Frequency Transformers

open access: yesCSEE Journal of Power and Energy Systems
A high frequency (HF) transformer is key equipment for dc-dc converter to achieve galvanic isolation and voltage transformation. As operating frequency increases, voltage and current transfer ratio of HF transformer may significantly deviate from the ...
Chen Liu, Lei Qi, Xiang Cui
doaj   +1 more source

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