Results 191 to 200 of about 292,173 (295)

A service evaluation of physiotherapy practice within one scottish intensive care unit [PDF]

, 2011
Salisbury, Lisa, Stevenson, Lorna
core  

SDPR–STK38 axis controls the proliferation–differentiation balance in alveolar type II cells

Animal Models and Experimental Medicine, EarlyView.
The present study identifies SDPR as a pivotal regulator orchestrating the balance between proliferation and differentiation in alveolar type II (AT2) cells. In SDPR+/+ cells, SDPR binds to and inhibits STK38 activity, thereby sustaining GSK‐3β signaling functionality to promote cyclin D1 degradation and maintain cell cycle homeostasis.
Jie Wang, Xuepei Lei, Yiying Huang, Jiaming Tang, Guiying Shi, Hang Li, Lin Bai   +6 more
wiley   +1 more source

Dose‐dependent pathogenicity and inflammatory imbalance in severely immunodeficient mice infected with mpox virus

Animal Models and Experimental Medicine, EarlyView.
This study establishes an NPG (NOD.Cg‐Prkdcscid Il2rgtm1/Vst) mouse model for severe monkeypox virus infection in immunocompromised hosts, demonstrating dose‐dependent disease severity and revealing that unbalanced pro‐inflammatory cytokine release drives pathogenesis, providing insights for therapeutic interventions. Abstract The global spread of mpox
Na Li, Ziqing Jia, Zhe Cong, Jianrong Ma, Jiahan Lu, Yongzhi Hou, Fei Wang, Jiasen Yang, Ting Chen, Jingjing Zhang, Dong Zhang, Jing Xue   +11 more
wiley   +1 more source

Xylazine exacerbates fentanyl-induced respiratory depression and prevents rescue by naloxone in mice. [PDF]

Psychopharmacology (Berl)
Watkins JM, Hahn R, Dempsey M, Hohmann AG.   +3 more
europepmc   +1 more source

Blood Lactate as a Prognostic Biomarker for Survival and Weight Loss in Amyotrophic Lateral Sclerosis: An Exploratory–Validation Study

Annals of Neurology, EarlyView.
Objective Lactate is increasingly recognized as an energy substrate, but its relevance to amyotrophic lateral sclerosis (ALS) remains unclear. We examined whether blood lactate is associated with survival and weight loss in ALS. Methods This retrospective study included an Australian exploratory cohort and a Japanese validation cohort with clinical ...
Ryutaro Nakamura, Frederik J. Steyn, Shuhei Kobashi, Nobuhiro Ogawa, Akihiro Kitamura, Isamu Yamakawa, Robert D. Henderson, Shyuan T. Ngo, Makoto Urushitani   +8 more
wiley   +1 more source

Research on Evaporation Characteristics and Safe Storage Duration of Marine Liquid Hydrogen Storage Tanks Under the Coupling Effect of Heat Leakage and Sloshing

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Liquid hydrogen, a zero‐carbon and high–energy‐density fuel, is a promising option for future oceangoing vessels. During maritime transportation, onboard cryogenic tanks are exposed to ambient heat leakage and ship‐induced roll motion, which can trigger sloshing and fundamentally modify the coupled thermo‐fluid processes governing boil‐off and
Yan Deng, Wenfeng Wu, Zhenyu Zhao, Rongsheng Lin, Liangyi Sun, Youfei Liu   +5 more
wiley   +1 more source

Indoor window ventilation and anxiety symptoms among older adults with disabilities in China: A cross-sectional study. [PDF]

Medicine (Baltimore)
Zhang Q, Zheng Q, Huang Z, Xu T.
europepmc   +1 more source

Design of Experiments‐Based Optimization of Recovered Carbon Black–Reinforced Isobutylene–Isoprene Rubber in Comparison With Conventional Carbon Black Systems

Journal of Applied Polymer Science, EarlyView.
Optimized potential of rCB via DOE: recovered carbon black from end‐of‐life tires was assessed as a full substitute for conventional carbon black in IIR composites. DOE and response surface methodology optimized rCB loading, plasticizer, and sulfur contents. Hardness showed linear trends, while rupture energy was nonlinear.
Vinícius Guedes Gobbi, Ester Costa de Almeida, Roberta Helena Mendonça, Marysilvia Ferreira da Costa   +3 more
wiley   +1 more source

Effects of Controlled Atmosphere Conditions on the Quality Characteristics, Physicochemical and Antioxidant Properties of Pork Bone Broth. [PDF]

Foods
Su Y, Dong J, Deng Q, Zhang L, Li J, Chen J.   +5 more
europepmc   +1 more source