Results 51 to 60 of about 18,208,739 (219)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Dissociation of sensitivity to spatial frequency in word and face preferential areas of the fusiform gyrus [PDF]

, 2011
Different cortical regions within the ventral occipitotemporal junction have been reported to show preferential responses to particular objects.
Woodhead, Z, Richard James Surtees Wise, Leech, R, Wise, Richard James Surtees, Marty Sereno, Robert Leech, Sereno, Marty, Surtees Wise, R.J., Sereno, Martin I., Woodhead, Z.V.J., Sereno, M, Woodhead, Zoe Victoria Joan, Zoe Victoria Joan Woodhead, Leech, Robert, Wise, RJS   +14 more
core   +1 more source

Bayesian estimation‐based sentiment word embedding model for sentiment analysis

CAAI Transactions on Intelligence Technology, 2022
Sentiment word embedding has been extensively studied and used in sentiment analysis tasks. However, most existing models have failed to differentiate high‐frequency and low‐frequency words.
Jingyao Tang, Yun Xue, Ziwen Wang, Shaoyang Hu, Tao Gong, Yinong Chen, Haoliang Zhao, Luwei Xiao   +7 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

What are the collocational exemplars of high-frequency English vocabulary? on identifying Mwus most representative of high-frequency, lemmatized concgrams [PDF]

, 2016
Collocations, simply defined, are words that have a high frequency of co-occurrence (Biber et al., 1999: Shin, 2006). Collocational fluency is an essential aspect of communicating in and comprehending a second language in a native-like fashion.
Rogers, James M.
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Validating the Effectiveness of Fine-Tuning for Semantic Classification of Japanese Katakana Words: An Analysis of Frequency and Polysemy Effects on Accuracy

Big Data and Cognitive Computing
In semantic classification of katakana words using large language models and pre-trained language models, semantic divergences from original English meanings, such as those found in Wasei-Eigo which is Japanese-made English, and the inherent sense ...
Kazuki Kodaki, Minoru Sasaki
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Processing advantage for emotional words in bilingual speakers [PDF]

, 2015
Effects of emotion on word processing are well established in monolingual speakers. However, studies that have assessed whether affective features of words undergo the same processing in a native and non-native language have provided mixed results ...
Rodriguez-Cuadrado, Sara, Vinson, David, Vigliocco, Gabriella, Vinson, Dave P., Vigliocco, G, Costa, Albert, 1970-, Vinson, D, Rodríguez-Cuadrado, S, Fox, N, Ponari, Marta, Costa, Albert, Rodríguez Cuadrado, Sara, 1984-, Costa, A, Fox, Neil, Ponari, M   +14 more
core   +1 more source

High-frequency words in academic spoken English: Corpora and learners [PDF]

, 2020
EAP teachers and course designers usually assume that learners have already mastered the most frequent words of general language before entering their courses.
Dang, TNY
core   +1 more source