Results 51 to 60 of about 132,751 (338)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Therapeutic ultrasound transducer technology and monitoring techniques: a review with clinical examples

International Journal of Hyperthermia
The exponential growth of therapeutic ultrasound applications demonstrates the power of the technology to leverage the combinations of transducer technology and treatment monitoring techniques to effectively control the preferred bioeffect to elicit the ...
Maxime Lafond, Allison Payne, Cyril Lafon   +2 more
doaj   +1 more source

A portable high-intensity focused ultrasound system for the pancreas with 3D electronic steering: a preclinical study in a swine model [PDF]

Ultrasonography, 2018
Purpose The aim of this animal study was to evaluate the safety and feasibility of a portable, ultrasonography-guided, high-intensity focused ultrasound (USg-HIFU) system to treat the pancreas. Methods Eight swine were included.
Won Chang, Jae Young Lee, Jae Hwan Lee, Jae Seok Bae, Yeon Jin Cho, Kook Jin Kang, Keonho Son, Yul Ri Chung, Kyoung Bun Lee, Joon Koo Han   +9 more
doaj   +1 more source

A Responsive Mesoporous Silica Nanoparticle Platform for Magnetic Resonance Imaging-Guided High-Intensity Focused Ultrasound-Stimulated Cargo Delivery with Controllable Location, Time, and Dose.

Journal of the American Chemical Society, 2019
Magnetic resonance imaging (MRI) is an essential modality for clinical diagnosis and MRI-guided high-intensity focused ultrasound (MRgHIFU) is a powerful technology for targeted therapy. Clinical applications of MRgHIFU primarily utilize hyperthermia and
Chi-An Cheng, Wei Chen, Le Zhang, Holden H. Wu, J. Zink   +4 more
semanticscholar   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Noninvasive Monitoring of Tissue Temperature Changes Induced by Focused Ultrasound Exposure using Sparse Expression of Ultrasonic Radio Frequency Echo Signals

Journal of Medical Signals and Sensors
Background: Noninvasive therapies such as focused ultrasound were developed to be used for cancer therapies, vessel bleeding, and drug delivery. The main purpose of focused ultrasound therapy is to affect regions of interest (ROI) of tissues without any ...
Kiarash Behnam Malekzadeh, Hamid Behnam, Jahangir (Jahan) Tavakkoli   +2 more
doaj   +1 more source

Adverse events of extracorporeal ultrasound-guided high intensity focused ultrasound therapy.

PLoS ONE, 2011
BackgroundHigh-intensity focused ultrasound (HIFU) is considered to be an alternative to surgery. Extracorporeal ultrasound-guided HIFU (USgFU) has been clinically used to treat solid tumors.
Tinghe Yu, Jun Luo
doaj   +1 more source

Assessment of Skin in Patients With Systemic Sclerosis Using High‐Frequency Ultrasound and Shear Wave Elastography: A Comparative Study With Histology, Molecular, and Clinical Parameters

Arthritis Care &Research, EarlyView.
Objective Ultrasound (US) has been proposed as a potential tool for assessing skin fibrosis in systemic sclerosis (SSc). However, a large‐scale comparison of US‐based assessment with histologic markers of skin fibrosis has not been reported. We evaluated US‐based skin assessments for their face validity (differentiation between involved SSc and healthy
Ruhani Desai, Filemon Tan, Minghua Wu, Jeffery L. Browning, Samuel Theodore, Meng Zhang, Brian Skaug, Harshdeep Singh Chawla, Manmohan Singh, Salavat Aglyamov, Kirill V. Larin, Maureen Mayes, Shervin Assassi   +12 more
wiley   +1 more source

Custos diretos do tratamento de homens com câncer de próstata via High Intensity Focused Ultrasound [PDF]

, 2023
Pâmela Adalgisa Lopes da Silva, Antônio Fernandes Costa Lima   +1 more
openalex   +1 more source

High-intensity focused ultrasound-induced mechanochemical transduction in synthetic elastomers

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance One challenge in exploiting polymer mechanochemistry in biological and clinical regimes is the lack of a compatible triggering system that enables noninvasive, spatiotemporal control of mechanochemical transformations.
Gun-Bae Kim, V. M. Lau, Abigail J Halmes, M. Oelze, Jeffrey S. Moore, King C. Li   +5 more
semanticscholar   +1 more source