Theoretical investigation of transgastric and intraductal approaches for ultrasound-based thermal therapy of the pancreas. [PDF]
BackgroundThe goal of this study was to theoretically investigate the feasibility of intraductal and transgastric approaches to ultrasound-based thermal therapy of pancreatic tumors, and to evaluate possible treatment strategies.MethodsThis study ...
Adams, Matthew S+4 more
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Distinct immune signatures in directly treated and distant tumors result from TLR adjuvants and focal ablation. [PDF]
Both adjuvants and focal ablation can alter the local innate immune system and trigger a highly effective systemic response. Our goal is to determine the impact of these treatments on directly treated and distant disease and the mechanisms for the ...
Borowsky, Alexander D+13 more
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A portable high-intensity focused ultrasound device for noninvasive venous ablation [PDF]
Varicose veins and other vascular abnormalities are common clinical entities. Treatment options include vein stripping, sclerotherapy, and endovenous laser treatment, but all involve some degree of invasive intervention. The purpose of this study was to determine ex vivo the effectiveness of a novel hand-held, battery-operated, high-intensity focused ...
Allie M. Sohn+6 more
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The Influence of Oxytocin on the Blood Perfusion of Uterine Fibroids: Contrast-enhanced Ultrasonography Evaluation [PDF]
BackgroundHigh intensity focused ultrasound ablation is a new technique for the treatment of uterine fibroids. Its efficacy is influenced by the blood perfusion of the fibroids.
Ren, Dehong, Wang, Wei, Wang, Yang
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A Surgical Perspective on Targeted Therapy of Hepatocellular Carcinoma. [PDF]
Hepatocellular carcinoma (HCC), the second leading cause of cancer deaths worldwide, is difficult to treat and highly lethal. Since HCC is predominantly diagnosed in patients with cirrhosis, treatment planning must consider both the severity of liver ...
Busuttil, Ronald W+2 more
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Modifying Ultrasound Waveform Parameters to Control, Influence, or Disrupt Cells [PDF]
Ultrasound can be focused into deep tissues with millimeter precision to perform non-invasive ablative therapy for diseases such as cancer. In most cases, this ablation uses high intensity ultrasound to deposit non-selective thermal or mechanical energy ...
Mittelstein, David Reza
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Thermal Ablation as an Alternative to Standard Breast Conserving Surgery in the Treatment of Invasive Ductal Carcinoma of the Elderly [PDF]
An aging population means an inevitable increase in cancer diagnoses, and thus, a novel solution is needed to address this looming problem. Within the field of breast cancer, thermal ablation has emerged as a promising alternative to surgical excision ...
Ducharme, Dani
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Image-Guided High-Intensity Focused Ultrasound, A Novel Application for Interventional Nuclear Medicine? [PDF]
Image-guided high-intensity focused ultrasound (HIFU) has been increasingly used in medicine over the past few decades, and several systems for such have become commercially available. HIFU has passed regulatory approval around the world for the ablation
Bailis, Nikolaos+5 more
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High-intensity focused ultrasound ablation for advanced pancreatic cancer
The aim of this study was to evaluate the efficacy, safety, and survival factors of high-intensity focused ultrasound (HIFU) ablation in the treatment of advanced pancreatic cancer.A retrospective analysis was conducted between September 2010 and March 2016.
Ke Ma+5 more
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High intensity focused ultrasound in clinical tumor ablation
Recent advances in high intensity focused ultrasound (HIFU), which was developed in the 1940s as a viable thermal tissue ablation approach, have increased its popularity. In clinics, HIFU has been applied to treat a variety of solid malignant tumors in a well-defined volume, including the pancreas, liver, prostate, breast, uterine fibroids, and soft ...
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