Results 111 to 120 of about 27,040,870 (237)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Hamilton Junior High School Highlights 1973
, 2016 The annual publication of the students of Hamilton Junior High, Lethbridge, Alberta.(1972-73)pdfHAMILTON JUNIOR HIGH YEARBOOK 1972.-1973PRINCIPALS MESSAGE MR. S. K.
Hamilton Junior High
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The annual publication of the students of W. R. Myers High School Taber, Alberta. (Volume 1977-1978)pdfW.R. Myers Taber, Alberta TABLE OF CONTENTS introduction 1 students 17 administration 34 sports 39 clubs and activities 53 graduation 74 conclusion 85 ...
W. R. Myers High School
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Victoria Park High School 2011
, 2022 The annual publication of the students of Victoria Park High School, Lethbridge, Alberta. (Volume. 2010-11)pdfGRADE 11 Aubree Adams Mercedes Atwood Nikolina Blatancic Sonia Cabrera Taylor Day Kirsten Gerard Aaron Gerk Dini Gesinghaus Cheyenne Haug ...
Victoria Park High School
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FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 1976 Yearbook for Lincoln High School in Port Arthur, Texas, which includes photographs of and information about the school, student body, teachers, and organizations.
Lincoln High School
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FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source