Results 81 to 90 of about 21,375,197 (296)

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz   +9 more
wiley   +1 more source

On the Algebraic Structure of Petri Nets

open access: yes, 2000
This paper retraces, collects, and summarises the contributions of the author --- both individually and in collaboration with others --- on the theme of algebraic, compositional approaches to the semantics of Petri ...
Sassone, V.
core   +1 more source

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

open access: yesAdvanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett   +7 more
wiley   +1 more source

A High-Level Petri Net Framework for Genetic Regulatory Networks

open access: yesJournal of Integrative Bioinformatics, 2007
To understand the function of genetic regulatory networks in the development of cellular systems, we must not only realise the individual network entities, but also the manner by which they interact.
Banks Richard, Steggles L. Jason
doaj   +1 more source

Biphasic Co‐Delivery of Curcumin and 5‐FU using 3D‐Printed Dissolving Microneedles for Skin Cancer Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
Using pixel‐aware digital light processing, the authors created high‐resolution, dissolvable microneedles from a PEGDA/VP matrix. These microneedles encapsulate curcumin and 5‐fluorouracil and dissolve in the skin, co‐delivering drugs directly to tumours.
Rutuja N. Meshram, Dimitrios A. Lamprou
wiley   +1 more source

UML and Petri Nets for Design and Analysis of Distributed Systems [PDF]

open access: yes, 2000
This paper presents a modification to UML to improve the modelling and analysis of discrete-event dynamic system (DEDS) representations of manufacturing systems.
Giacomini, Luisa   +2 more
core   +1 more source

A formal approach towards IoT-enabled mechanism for digital polio system using Colured Petri Net

open access: yesEgyptian Informatics Journal
Polio remains an extreme health challenge in numerous weak and high-risk regions such as Pakistan, Afghanistan, Nigeria mainly due to ineffective monitoring and the lack of integrated digital systems for immunization organization and management.
Shahbaz Ahmad   +4 more
doaj   +1 more source

Enhanced Architecture for Privacy Preserving Data Integration in a Medical Research Environment

open access: yesIEEE Access, 2017
Recent advancement in digital and communication technologies has brought privacy aspects to the forefront. Although e-health has many advantages and it facilitates the patients and health service providers significantly, the possibility of privacy ...
Farhana Jabeen   +7 more
doaj   +1 more source

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

open access: yesAdvanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans   +7 more
wiley   +1 more source

Axiomatizing Petri Net Concatenable Processes [PDF]

open access: yes, 1995
The concatenable processes of a Petri net $N$ can be characterized abstractly as the arrows of a symmetric monoidal category $P[N]$. Yet, this is only a partial axiomatization, since $P[N]$ is built on a concrete, ad hoc chosen, category of symmetries ...
Sassone, V.
core   +2 more sources

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