Results 131 to 140 of about 3,164,376 (236)

GDP‐fucose transporter SLC35C1: a potential regulatory role in cytosolic GDP‐fucose and fucosylated glycan synthesis

FEBS Open Bio, EarlyView.
The inactivation of SLC35C1 (GDP‐fucose transporter) and enzymes involved in GDP‐fucose biosynthesis was studied. Fucose supplementation increases the level of GDP‐fucose to abnormal, millimolar values in the absence of the TSTA3 protein and SLC35C1 in contrast to the GMDS/SLC35C1 double mutant.
Edyta Skurska, Mariusz Olczak
wiley   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

A review of artificial intelligence in brachytherapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy.
Jingchu Chen, Richard L. J. Qiu, Tonghe Wang, Shadab Momin, Xiaofeng Yang   +4 more
wiley   +1 more source

The interaction between social determinants of schizophrenia and brain dopamine circuitry. [PDF]

World Psychiatry
Selten JP, Schalbroeck R, Booij J.
europepmc   +1 more source

Evaluating the use of diagnostic CT with flattening filter free beams for palliative radiotherapy: Dosimetric impact of scanner calibration variability

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Palliative radiotherapy comprises a significant portion of the radiation treatment workload. Volumetric‐modulated arc therapy (VMAT) improves dose conformity and, in conjunction with flattening filter free (FFF) delivery, can decrease treatment times, both of which are desirable in a population with a high probability of retreatment ...
Madeleine L. Van de Kleut, Lesley A. Buckley, Elsayed S. M. Ali   +2 more
wiley   +1 more source

Componential modeling of argumentative essay writing from multiple online sources: a Bayesian network approach. [PDF]

Front Psychol
Singh A, Sun Y, Alexander PA, Zhao H.
europepmc   +1 more source

Toward a human‐centric co‐design methodology for AI detection of differences between planned and delivered dose in radiotherapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Introduction Many artificial intelligence (AI) solutions have been proposed to enhance the radiotherapy (RT) workflow, but limited applications have been implemented to date, suggesting an implementation gap. One contributing factor to this gap is a misalignment between AI systems and their users.
Luca M. Heising, Frank Verhaegen, Stefan G. Scheib, Maria J. G. Jacobs, Carol X. J. Ou, Viola Mottarella, Yin‐Ho Chong, Mariangela Zamburlini, Sebastiaan M. J. J. G. Nijsten, Ans Swinnen, Michel Öllers, Cecile J. A. Wolfs   +11 more
wiley   +1 more source

Quantification and dosimetric impact of intra‐fractional bladder changes during CBCT‐guided online adaptive radiotherapy for pelvic cancer treatments

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose This study quantitatively evaluates bladder changes and their dosimetric impact during the on‐couch adaptive process on a commercial CBCT‐based online adaptive radiotherapy (CT‐gART) platform. Methods Data from 183 fractions of ten patients receiving online ART for pelvic cancers were analyzed retrospectively.
Ingrid Valencia Lozano, Elizabeth Buss, Catherine S. Spina, David P. Horowitz, Lisa A. Kachnic, Michael Price, Yi‐Fang Wang, Reshma Munbodh   +7 more
wiley   +1 more source

Multi-omics analysis of the mechanisms of abundant theacrine and EGCG3"Me in tea (Camellia sinensis). [PDF]

BMC Plant Biol
Zhu Y, Gu M, Yu W, Liao L, Gao S, Wang S, Lin H, Gui W, Zhou Y, Chen Z, Zeng J, Ye N.   +11 more
europepmc   +1 more source

Fast, automated optimization of virtual monoenergetic images with the dual‐energy image synthesizer for cone‐beam CT

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background Dual‐energy cone‐beam CT (DE‐CBCT) has become subject of recent interest due to the ability to produce virtual monoenergetic images (VMIs) with improved soft‐tissue contrast and reduced nonuniformity artifacts. However, efficient production and optimization of VMIs remains an under‐explored part of DE‐CBCT's application.
Andrew Keeler, Jason Luce, Mathias Lehmann, John C. Roeske, Hyejoo Kang   +4 more
wiley   +1 more source