Results 21 to 30 of about 3,164,376 (236)

Layout area models for high-level synthesis [PDF]

open access: yes, 1991
Traditionally, the common cost functions, the number of functional units, registers and selector inputs, are used in high level synthesis as quality measures. However, these traditional design quality measures may not reflect the real physical design. To
Chaiyakul, Viraphol   +2 more
core  

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Layout-driven allocation for high level synthesis [PDF]

open access: yes, 1991
We propose a hypergraph model and a new algorithm for hardware allocation. The use of a hypergraph model facilitates the identification of sharable resources and the calculation of interconnect costs.
Gajski, Daniel D., Wu, Allen C.H.
core  

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Bridging high-level synthesis to RTL technology libraries [PDF]

open access: yes, 1991
The output of high-level synthesis typically consists of a netlist of generic RTL components and a state sequencing table. While module generators and logic synthesis tools can be used to map RTL components into standard cells or layout geometries, they ...
Dutt, Nikil D., Kipps, James R.
core  

An empirical evaluation of High-Level Synthesis languages and tools for database acceleration [PDF]

open access: yes, 2014
High Level Synthesis (HLS) languages and tools are emerging as the most promising technique to make FPGAs more accessible to software developers. Nevertheless, picking the most suitable HLS for a certain class of algorithms depends on requirements such ...
Arcas Abella, Oriol   +9 more
core   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

GENUS : a generic component library for high level synthesis [PDF]

open access: yes, 1988
This report describes the organization of GENUS, a generic component library for high level synthesis. Generic components and instances in GENUS are organized into hierarchical classes, with the component type stored at the root of the hierarchy, and ...
Dutt, Nikil D.
core  

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