Results 41 to 50 of about 3,164,376 (236)
High-level Synthesis Integrated Verification [PDF]
Engineering, Technology & Applied Science Research, 2015 It is widely known in the engineering community that more than 60% of the IC design project time is spent on verification. For the very complex contemporary chips, this may prove prohibitive for the IC to arrive at the correct time in the market and therefore, valuable sales share may be lost by the developing industry.
openaire +3 more sources
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Memory-Based High-Level Synthesis Optimizations Security Exploration on the Power Side-Channel [PDF]
, 2020 High-level synthesis (HLS) allows hardware designers to think algorithmically and not worry about low-level, cycle-by-cycle details. This provides the ability to quickly explore the architectural design space and tradeoffs between resource utilization ...
Blackstone, Jeremy +5 more
core
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Adaptation to G93A superoxide dismutase 1 in a motor neuron cell line model of amyotrophic lateral sclerosis. The role of glutathione [PDF]
, 2009 Motor neuron degeneration in amyotrophic lateral sclerosis involves oxidative damage. Glutathione (GSH) is critical as an antioxidant and a redox modulator.
AND LAVINIA CANTONI +5 more
core +1 more source
FEBS Letters, EarlyView.Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston +7 more
wiley +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
The cardiomyocyte "redox rheostat": Redox signalling via the AMPK-mTOR axis and regulation of gene and protein expression balancing survival and death. [PDF]
, 2019 Reactive oxygen species (ROS) play a key role in development of heart failure but, at a cellular level, their effects range from cytoprotection to induction of cell death.
Clerk, A +9 more
core +3 more sources
A formal framework for high level synthesis [PDF]
, 1995 In this paper, we propose a new approach to formal synthesis which focuses on the generation of verification-friendly circuits. Starting from a high-level implementation description, which may result from the application of usual scheduling and allocation algorithms, hardware is automatically synthesized.
Kropf, Thomas +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source