Results 61 to 70 of about 317,795 (294)

HACPar: An efficient parallel multiscale framework for hybrid atomistic–continuum simulation at the micro- and nanoscale

Advances in Mechanical Engineering, 2017
The hybrid atomistic–continuum coupling method based on domain decomposition serves as an important tool for the microfluidic simulation. However, major modifications to existing codes are often required to enable such simulations, which pose significant
Xiao-Guang Ren, Qian Wang, Li-Yang Xu, Wen-Jing Yang, Xin-Hai Xu   +4 more
doaj   +1 more source

Traffic Sign Detection Method Based on Improved SSD

Information, 2020
Due to changes in illumination, adverse weather conditions, and interference from signs similar to real traffic signs, the false detection of traffic signs is possible. Nevertheless, in order to improve the detection effect of small targets, baseline SSD
Shuai You, Qiang Bi, Yimu Ji, Shangdong Liu, Yujian Feng, Fei Wu   +5 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Discovering Domain-Agnostic Fake News Detectors Through Deep Self-Supervised Learning

IEEE Access
The rapid spread of misinformation across online platforms poses a major threat to societal trust, public health, and democratic processes. While recent advances in machine learning have improved the accuracy of fake news detection, most existing ...
Carmela Comito, Massimo Guarascio, Angelica Liguori, Giuseppe Manco, Francesco Sergio Pisani   +4 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Ensemble of rankers for efficient gene signature extraction in smoke exposure classification

BMC Bioinformatics, 2018
Background System toxicology aims at understanding the mechanisms used by biological systems to respond to toxicants. Such understanding can be leveraged to assess the risk of chemicals, drugs, and consumer products in living organisms.
Maurizio Giordano, Kumar Parijat Tripathi, Mario Rosario Guarracino   +2 more
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

xLSTM-Based Urban Traffic Flow Prediction for Intelligent Transportation Governance

Applied Sciences
Urban traffic congestion poses persistent challenges to mobility, public safety, and governance efficiency in metropolitan areas. This study proposes an intelligent traffic flow forecasting framework based on an extended Long Short-Term Memory (xLSTM ...
Chung-I Huang, Jih-Sheng Chang, Jun-Wei Hsieh, Jyh-Horng Wu, Wen-Yi Chang   +4 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source