Mepce Restrains Ferroptosis in Prostate Cancer Through 7SK–P‐TEFb Pause Control
Genome‐wide CRISPR screening identifies MEPCE as a pause‐control regulator that restrains ferroptosis in prostate cancer. MEPCE loss releases P‐TEFb/CDK9 from 7SK snRNP control, enhances RNAPII Ser2 phosphorylation, and accelerates NRF2‐HMOX1‐driven labile iron accumulation and lipid peroxidation, revealing a transcriptional kinetic gate that lowers ...
Tongtong Zhang +9 more
wiley +1 more source
Sustainable high-performance concrete: harnessing recycled rubber and slag for strength and eco-friendliness. [PDF]
Bahmani H, Mostafaei H.
europepmc +1 more source
Self‐Assembly of Organic–Inorganic Copolymers Toward Bio‐Inspired Cementitious Composites
Organic–inorganic copolymerization of calcium silicate hydrate and thioctic acid produces a self‐organized nanocomposite inspired by the disordered collagen–mineral architecture of trabecular bone. The resulting material combines a compressive strength above 300 MPa with intrinsic physical reprocessibility, retaining over 80% of its strength and energy
Zonglin Xie +8 more
wiley +1 more source
Rehabilitation of concrete structures using Ultra-High Performance Fibre Reinforced Concrete [PDF]
An original concept is presented for the rehabilitation of concrete structures. The main idea is to use Ultra-High Performance Fibre Reinforced Concrete (UHPFRC) to “harden” those zones where the structure is exposed to severe environmental and high ...
Brühwiler, E., Denarié, E.
core +1 more source
Data-driven optimisation of sustainable high-performance concrete incorporating SCMs, biomass ash, and graphene nanoplatelets. [PDF]
Anand P +4 more
europepmc +1 more source
Thermodynamics and Kinetics in Host Design for Dendrite‐Free Zinc Metal Anodes
This review comprehensively summarizes recent advances in host design strategies for high‐performance zinc metal anodes, and deeply elucidates their thermodynamic and kinetic design principles from the perspective of surface modification, interface engineering, and spatial confinement.
Peng Xiao Sun +9 more
wiley +1 more source
Properties and Synergistic Mechanism of Ultra-High-Performance Concrete Incorporating Spontaneous Combustion Gangue (Sand) and Phosphorus Slag. [PDF]
Zhang Y +7 more
europepmc +1 more source
A Multiscale Mechanistic Framework for Polydopamine Dyeing in Ultrablack Wool Textiles
Ultrablack photonic textiles are enabled through polydopamine (PDA) dyeing, which is governed by the interplay of PDA chemistry, wool surface topology and chemistry, and hierarchical fiber–yarn–fabric architecture. Fabric architecture emerges as a primary and previously underappreciated design lever for wide‐angle optical performance.
Hansadi Jayamaha +4 more
wiley +1 more source
Rheology, strength and durability performance of bentonite-enhanced high-performance concrete. [PDF]
Reddy MAK, Khed VC, Kavuri NC.
europepmc +1 more source
An optimized Cas9‐enriched nanopore sequencing workflow, combined with STRiker, enables simultaneous analysis of disease‐associated STR loci from patient blood. The nCATS–STRiker workflow detects repeat expansions, de novo repeat motifs, interruption patterns, and methylation in a single assay, improving the genetic diagnosis of previously undiagnosed ...
Seungbok Lee +11 more
wiley +1 more source

