Nanometer Layer Coating to Lactose Particles for Optimization of Dexamethasone Pulmonary Delivery
Nanometer layer coating (NLC) was investigated and its mechanism illustrated by advanced characterization techniques. The effects and application for the inhalation of dexamethasone (DEX) were demonstrated through in vitro and in vivo evaluation. This approach increased DEX bioavailability and enabled the dose to be reduced to 1/30 of the intravenous ...
Qin Nie +11 more
wiley +1 more source
Machine learning-assisted evolutionary optimization of hole quality and surface integrity in abrasive waterjet drilling of polycarbonate. [PDF]
Chandar JB +5 more
europepmc +1 more source
Local Solvent Ordering Drives Supramolecular Chirality Inversion
Local solvent organization is shown to govern supramolecular chirality by selecting distinct chiral assembly pathways. A subtle change in water‐DMSO composition reverses the helical sense of a chiral perylene bisimide, while heating induces an irreversible thermal inversion to a more stable enantiomorph.
Triza Pal +4 more
wiley +1 more source
Evolution of jets generated by noncircular nozzles with varying aspect ratios. [PDF]
Haiyan Z +4 more
europepmc +1 more source
Paraborg: Paramedic Cyborg Insects for In Situ Emergency Drug‐Delivery
This work introduces Paraborg, a human‐supervised paramedic cyborg‐insect platform that combines controllable locomotion, onboard imaging, and an auto‐injection mechanism for in situ drug‐delivery. By demonstrating reliable navigation, target stabilization, injector launch, and multi‐insect teamwork, the study extends cyborg insects from survivor ...
H. Nhan Le +5 more
wiley +1 more source
Bio‐Inspired Gradient Coatings Enhance the Leading Edge Erosion Resistance of Wind Blades
Rain‐induced erosion of the wind turbine blade leading edge poses a critical challenge to maintenance and operation. Here, we propose a bio‐inspired approach for erosion protection utilising a platelet‐reinforced polyurethane coating with a graded through‐thickness architecture.
Natalia Sofia Guevara‐Sotelo +2 more
wiley +1 more source
Novel Design in Venturi-Type Nozzle by Selective Laser Melting for Enhancement in Microbubble Generation. [PDF]
Chung M, Park C.
europepmc +1 more source
A straightforward method is introduced to produce ion‐gel films with very low surface roughness by employing a solution‐shearing coating process. These ion‐gel films permit the growth of crystalline thin films of various small molecule organic semiconductor molecules directly on top of the ion‐gel layer, thereby enabling “inverted” small molecule ...
Jonathan Perez Andrade +10 more
wiley +1 more source
Optimization of Mechanical Structure for Pomegranate Peeling and Low-Damage Seed Extraction Technology Based on Mechanical Property Analysis: A Comprehensive Review. [PDF]
Zhu E, Ran J, Li L, Zhu J.
europepmc +1 more source
Improved Direct Ink Writing of Liquid Metal Foams via Liquid Additives
The ability to pattern liquid metal is useful for making soft electrical and thermal devices. Dispensing liquid metal from a nozzle naturally results in the formation of spheroidal droplets, making direct‐write printing challenging. Liquid metal foams containing pockets of air can extrude as filaments, albeit inconsistently.
Febby Krisnadi +3 more
wiley +1 more source

