Results 151 to 160 of about 2,007,040 (267)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Development and validation of a high-resolution hyperspectral imaging system for the retina. [PDF]

J Biomed Opt
Tran MH, Pruitt K, Bryarly M, Emordi I, Ali A, Ma L, Fei B.   +6 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Synchrotron Radiation-Based FTIR Microspectroscopic Imaging of Traumatically Injured Mouse Brain Tissue Slices

ACS Omega, 2020
Yuansen Guo, Tunan Chen, Shi Wang, Xiaojie Zhou, Hua Zhang, Dandan Li, Ning Mu, Mingjie Tang, Meidie Hu, Dongyun Tang, Zhongbo Yang, Jiajia Zhong, Yuzhao Tang, Hua Feng, Xuehua Zhang, Huabin Wang   +15 more
doaj   +1 more source

A high-resolution daily CO₂ dataset for China (2016-2020). [PDF]

Sci Data
Yuan Z, Liu Y, Yang A, Wang D.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

High-resolution whole-brain magnetic resonance spectroscopic imaging in youth at risk for psychosis. [PDF]

Imaging Neurosci (Camb)
Céléreau E, Lucchetti F, Alemán-Gómez Y, Dwir D, Cleusix M, Ledoux JB, Jenni R, Conchon C, Bach Cuadra M, Schilliger Z, Solida A, Armando M, Plessen KJ, Hagmann P, Conus P, Klauser A, Klauser P.   +16 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Interferometric ultra-high resolution 3D imaging through brain sections. [PDF]

Nat Commun
Gao HC, Xu F, Cheng X, Chen T, Bi C, Zheng Y, Li Y, Li Y, Chubykin AA, Huang F.   +9 more
europepmc   +1 more source