Results 41 to 50 of about 676,481 (295)

Atomic-scale imaging of a 27-nuclear-spin cluster using a single-spin quantum sensor

, 2019
Nuclear magnetic resonance (NMR) is a powerful method for determining the structure of molecules and proteins. While conventional NMR requires averaging over large ensembles, recent progress with single-spin quantum sensors has created the prospect of ...
Abobeih, M. H., Bakker, M. A., Bartling, H. P., Bradley, C. E., Degen, M. J., Markham, M., Randall, J., Taminiau, T. H., Twitchen, D. J.   +8 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

A Spectral-Scanning Magnetic Resonance Imaging (MRI) Integrated System [PDF]

, 2008
An integrated spectral-scanning magnetic resonance imaging (MRI) technique is implemented in a 0.12μm SiGe BiCMOS process. This system is designed for small-scale MRI applications with non-uniform and low magnetic fields.
Babakhani, Aydin, Hajimiri, Ali, Hassibi, Arjang   +2 more
core   +1 more source

An assessment on the incremental value of high-resolution magnetic resonance imaging to identify culprit plaques in atherosclerotic disease of the middle cerebral artery

European Radiology, 2015
ObjectiveAlthough certain morphological features depicted by high resolution, multi-contrast magnetic resonance imaging (hrMRI) have been shown to be different between culprit and non-culprit middle cerebral artery (MCA) atherosclerotic lesions, the ...
Z. Teng, Wenjia Peng, Q. Zhan, Xuefeng Zhang, Qi Liu, Shiyue Chen, X. Tian, Luguang Chen, Adam J. Brown, M. Graves, J. Gillard, Jianping Lu   +11 more
semanticscholar   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Submillimeter diffusion tensor imaging and late gadolinium enhancement cardiovascular magnetic resonance of chronic myocardial infarction. [PDF]

, 2017
BackgroundKnowledge of the three-dimensional (3D) infarct structure and fiber orientation remodeling is essential for complete understanding of infarct pathophysiology and post-infarction electromechanical functioning of the heart.
Bluemke, David A, Gai, Neville, Halperin, Henry, Herzka, Daniel A, McVeigh, Elliot R, Mori, Susumu, Pashakhanloo, Farhad, Trayanova, Natalia A, Zviman, Muz   +8 more
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Impact of incomplete ventricular coverage on diagnostic performance of myocardial perfusion imaging. [PDF]

, 2017
In the context of myocardial perfusion imaging (MPI) with cardiac magnetic resonance (CMR), there is ongoing debate on the merits of using technically complex acquisition methods to achieve whole-heart spatial coverage, rather than conventional 3-slice ...
Arsanjani, Reza, Berman, Daniel S, Dharmakumar, Rohan, Fish, Mathews B, Germano, Guido, Li, Debiao, Motwani, Manish, Sharif, Behzad, Slomka, Piotr   +8 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Pancoast Tumor: The Role of Magnetic Resonance Imaging

Case Reports in Radiology, 2013
We report imaging techniques in the definition of the therapeutic planning of a 65-year-old man with a diagnosis of Pancoast tumor. Computed Tomography has a pivotal role in the assessment of nodes involvement and distant metastasis.
Guglielmo Manenti, Mario Raguso, Silvia D'Onofrio, Simone Altobelli, Angela Lia Scarano, Erald Vasili, Giovanni Simonetti   +6 more
doaj   +1 more source