Results 141 to 150 of about 1,071,560 (337)

Are women over the age of 40 at risk for high-order multiple pregnancy when up to six conceptuses are replaced? [PDF]

, 2001
Eric Urcia, Lucinda L. Veeck
openalex   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

High perinatal risk in two ethnic groups during pregnancy: associations with the state of the system «Lipid Peroxidation-Antioxidant Defense»

, 2013
Lubov Iljinichna Kolesnikova, M. A. Darenskaya, Lyudmila Grebenkina, Natalia Protopopova, Maria Dolgikh   +4 more
openalex   +2 more sources

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

Advanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang, Shuang Li, Man Li, Wenke Zhou, Jianqing Zhang, Zhenfu Wu, Zhaoqi Mao, Juan Wan, Xinhao Tang, Baoping Zheng, Qiang Liu, Zhendong Li, Xiaobing Jiang, Qingping Wu, Youfan Ye, Haijun Wang   +15 more
wiley   +1 more source

Single- vs double-layer uterine closure of the cesarean scar in niche development: the Nicest StudyAJOG Global Reports at a Glance

AJOG Global Reports
BACKGROUND: There is an ongoing controversy regarding the optimal uterine closure technique for preventing niche development. Single- and double-layer closures have been considered comparable in terms of niche incidence after primary cesarean delivery ...
Ha Thi Thu Nguyen, PhD, Giang Thi Tra Duong, MD, Dat Tuan Do, PhD, Thuong Thi Huyen Phan, PhD, Duc Anh Tran, MD, Toan Khac Nguyen, MD, Anh Duy Nguyen, PhD   +6 more
doaj   +1 more source

Soluble Fibrin Monomer Complex and D-Dimer Concentrations Between Patients at Low and High Risk of Venous Thromboembolism Before Delivery According to RCOG Score Assessment: An Observational Study Among 100 Third-Trimester Vietnamese Pregnancies [PDF]

Anh Dinh Bao Vuong, Ngoc Hai Tran, Thanh Hai Pham, Long Ho Le, Phúc Nhơn Nguyễn   +4 more
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A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

Foetal gluten immunogenic peptides during pregnancy: a new determinant on the coeliac exposome

BMC Medicine
Background The increasing incidence of coeliac disease is leading to a growing interest in active search for associated factors, even the intrauterine and early life.
María de Lourdes Moreno, María González-Rovira, Cristina Martínez-Pancorbo, María Martín-Cameán, Ana María Nájar-Moyano, Mercedes Romero, Esther de la Hoz, Cristina López-Beltrán, Encarnación Mellado, José Luis Bartha, Petter Brodin, Alfonso Rodríguez-Herrera, José Antonio Sainz-Bueno, Carolina Sousa   +13 more
doaj   +1 more source

406 Cost-effectiveness of virtual Mindfulness Based Cognitive Therapy on pregnancies at high risk of perinatal depression [PDF]

Lindsay Quinn, Riane Bradbury-Huang, Ellen L. Tilden, Olivia J. Curl, Uma Doshi, Taylor Shank, Aaron B. Caughey   +6 more
openalex   +1 more source

FSTL1 Orchestrates Metabolic‐Epigenetic Crosstalk: Glycolysis‐Dependent H3K18 Lactylation Drives Cartilage Fibrosis in Osteoarthritis

Advanced Science, EarlyView.
FSTL1 promotes glycolysis during chondrocyte fibrosis by triggering the HIF‐1 signaling pathway, which causes lactate to accumulate. The buildup of lactate leads to changes in histone lysine lactylation, which in turn enhances the expression of genes associated with fibrosis.
Feng Lu, Yunyuan Yu, Guangrong Yin, Huiqun Hu, Shishuo Li, Yuting Tang, Yimin Liu, Maoyuan Li, Liang liang Wang, Chao Xu, Gongyin Zhao, Baojun Zhou, Yuji Wang   +12 more
wiley   +1 more source