Results 171 to 180 of about 3,042,424 (374)

Deciphering the Acetabular Labrum's Cellular Atlas: MDK Inhibition as a Novel Therapeutic Method for Developmental Dysplasia of the Hip

open access: yesAdvanced Science, EarlyView.
This study explores developmental dysplasia of the hip (DDH) by analyzing acetabular labrum abnormalities using single‐cell and spatial transcriptomics. Aberrant fibrocartilage stem cell proliferation is linked to DDH progression. Targeting the MK signaling pathway with a specific inhibitor effectively alleviates early DDH abnormalities, offering ...
Runze Yang   +10 more
wiley   +1 more source

Anthocyanins Prevent Mastitis Exacerbation by Inhibiting PANoptosis Activation

open access: yesAdvanced Science, EarlyView.
PANoptosis activation is an effective therapeutic target during mastitis progression, and Gasdermin D activation is key factor contributing to blood milk barrier damage during mastitis, while cyanidin 3‐O‐galactoside can inhibit these targets to exert a protective effect. Therefore, the extraction of key active ingredients from plants for the treatment
Rui Feng   +23 more
wiley   +1 more source

The Association Between Advanced Maternal Age and Short Interpregnancy Intervals on Preterm Labor [PDF]

open access: yes, 2019
Background: Preterm birth is the leading cause of neonatal and infant mortality and has become a major health concern due to the increasing rates of infant deaths in the United States (WHO, 2017). Studying maternal risk factors for preterm labor provides
Burns, Hannah N., DuChanois, Kristi L.
core   +1 more source

Foetal gluten immunogenic peptides during pregnancy: a new determinant on the coeliac exposome

open access: yesBMC Medicine
Background The increasing incidence of coeliac disease is leading to a growing interest in active search for associated factors, even the intrauterine and early life.
María de Lourdes Moreno   +13 more
doaj   +1 more source

Navigating the Storm: Managing Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT) in a High-Risk Pregnancy. [PDF]

open access: yesCureus, 2023
Proskuriakova E   +6 more
europepmc   +1 more source

Comparison of power Doppler and velocimetry in predicting outcome of high‐risk pregnancy [PDF]

open access: bronze, 2001
Mariusz Dubiel   +3 more
openalex   +1 more source

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

open access: yesAdvanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song   +17 more
wiley   +1 more source

A multicenter randomized controlled trial evaluating the effect of the use of an anti‐adhesion barrier for diverting ileostomy on the multidimensional workload in minimally invasive surgery for rectal cancer (YCOG 2005: The ADOBARRIER study)

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This multicenter, single‐blind, randomized, controlled trial was conducted to evaluate the multidimensional workload of the first operator during ileostomy closure using the SURG‐TLX between groups with and without the use of the spray‐type anti‐adhesion material during diverting ileostomy construction.
Emi Ota   +8 more
wiley   +1 more source

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