Senolytic Therapy as a Preventive Strategy for Spine Degeneration and Pain
Cellular senescence promotes inflammation, tissue degeneration, and chronic back pain. In sparc‐null mice, early oral administration of the senolytic agents o‐vanillin and RG‐7112 reduced senescent cell burden and pro‐inflammatory SASP signaling across intervertebral discs, endplates, vertebral bone, and spinal cord.
Saber Ghazizadeh +7 more
wiley +1 more source
Microstructure and mechanical properties of (Mg, Ce)-modified Al-7.5Si-15Cu-5Zn brazing joints on 5083 aluminum alloy. [PDF]
Wang Y +6 more
europepmc +1 more source
Hierarchically Soft Porous MOF‐Polymer Monolith for Fast and Large‐Scale Moisture Buffering
A soft, hierarchical porous monolith that combines metal–organic frameworks (MOFs) with a thermoresponsive polymer matrix enables rapid, large‐scale moisture buffering. The synergistic interface facilitates high‐capacity water capture and low‐energy release for sustainable indoor dehumidification.
Guangxin Ma +9 more
wiley +1 more source
Effect of Post-Sintering Shot Peening Treatment on the Corrosion Behavior of Alumix 321 Powder Metallurgy Alloy in 3.5 wt.% NaCl Solution. [PDF]
Ibrahim A, Bishop P, Kipouros G.
europepmc +1 more source
Sustainable Materials Design With Multi‐Modal Artificial Intelligence
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu +8 more
wiley +1 more source
This work provides a practical guide for neuroengineers to design advanced neural interfaces, embracing and tailoring the concept of functional disorder. By bridging 2D and 3D in vitro models, this work highlights how non‐periodic, spatially heterogeneous, multiscale nanotopography can enable more physiologically relevant platforms for studying neural ...
F. Maita +4 more
wiley +1 more source
Effects of Simulated Service Environments on the Microstructure and Interfacial Properties of Ceramic Fiber-Reinforced Al-Matrix Composites. [PDF]
Chu D +5 more
europepmc +1 more source
A rotational energy harvesting device that successfully reconciles high power density with mechanical durability through a hybrid sliding‐and‐bouncing kinematic mechanism is reported. The success reported in our paper includes addressing a dilemma where enhanced electrical output comes at the cost of increased friction and wear, limiting the practical ...
Yihong Lin +12 more
wiley +1 more source
Ultrasound-Assisted Processing of Aluminum Matrix Nanocomposites: Parameter Optimization for Enhanced Mechanical Properties. [PDF]
Takele YF +5 more
europepmc +1 more source
Acoustic plasmons in Ti3C2Tx MXene strongly compress infrared electromagnetic fields and enhance light–matter interactions at the nanoscale. This platform couples broadband plasmon excitations with molecular vibrations, enabling simultaneous sensing of high‐ and low‐frequency vibrational modes in ultrathin PMMA and graphene oxide films, and extending ...
Changhoon Park +7 more
wiley +1 more source

