Results 231 to 240 of about 16,685,753 (277)

Through the lens of marketing authorization holders: experience in use of real‐world data and real‐world evidence in drug development and regulatory submissions in EU

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this study was to assess the general and product‐specific experiences of MAHs use of RWD/RWE in medicines development and in their regulatory submissions, and to explore organizational aspects of MAHs related to RWD/RWE. Methods An electronic survey was conducted, and information collected directly from MAHs.
Sini M. Eskola   +5 more
wiley   +1 more source

When meta‐analyses mislead: Promises and pitfalls in teratology counselling

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Meta‐analysis has become a central tool for evidence synthesis in clinical teratology, offering the promise of increased statistical power, earlier signal detection and consolidated guidance for teratology counselling. When conducted rigorously and interpreted carefully, pooled analyses can provide clinicians with a structured basis for risk ...
Yusuf Cem Kaplan, Nusret Uysal
wiley   +1 more source

AI voice journaling for future language teachers: A path to well‐being through reflective practices

open access: yesBritish Educational Research Journal, EarlyView.
Abstract This study aimed to explore the perceived impact of using an AI‐powered voice journaling app in overcoming the challenges and stressors encountered by senior students enrolled in teaching practicum at an English Language Teaching Bachelor's programme.
Bora Demir, Duygu Özdemir
wiley   +1 more source
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Minimum Reinforcement in High‐Strength Concrete

Journal of Structural Engineering, 1990
A dimensional analysis criterion is proposed to compute the minimum amount of reinforcement for high‐strength concrete members in flexure. Such an amount is assumed to be provided by the condition of simultaneous first cracking aand steel yielding. The fracture mechanics model utilized defines a brittleness number NP, which is revealed to be a measure ...
BOSCO, CRESCENTINO   +2 more
openaire   +2 more sources

Shrinkage of High-strength Concrete and High-flowability Concrete

HKIE Transactions, 2010
Throughout the years, a large amount of research on the shrinkage of normal concrete with cube compressive strength up to 60 MPa has been carried out. Relatively, the amount of research on the shrinkage of high-strength concrete and high-flowability concrete is not as much.
Wong, HHC, Kwan, AKH, Fung, WWS
openaire   +2 more sources

High Strength Concrete in the Precast Concrete Industry

PCI Journal, 1993
The precast concrete industry has, since its inception, been a recognized leader in the development and use of high strength concrete. Yet in recent years, whereas concrete strength in building applications has increased from 6000-8000 psi to 12,000-16,000 psi, there has not been a corresponding trend in the strength of precast concrete. As part of its
Charles W. Dolan, Robert W. LaFraugh
openaire   +1 more source

Fracture analysis of a high-strength concrete and a high-strength steel-fiber-reinforced concrete

Mechanics of Composite Materials, 2007
This paper addresses the use of R-curves to study the fracture behavior of high-strength concrete and steel-fiber-reinforced concrete subjected to crack ing in a three-point bending configuration. The R-curves are modeled through an effective approach based on the equations of linear-elastic fracture mechanics (LEFM), which relates the applied load to ...
openaire   +1 more source

Ultra High Strength Concrete

PCI Journal, 1967
A COMMISSION WAS ESTABLISHED ON METHODS OF ACHIEVING HIGH- STRENGTH CONCRETE TO FIND OUT WHETHER THE EFFECTIVE COMPRESSIVE STRENGTH OF CONCRETE CAN BE SUBSTANTIALLY INCREASED SO THAT PRESTRESSED CONCRETE MAY BECOME NOT MERELY AN ECONOMIC STRUCTURAL MATERIAL OF ATTRACTIVE CHARACTERISTICS, BUT A MATERIAL OF HIGH SPECIFIC STRENGTH AS WELL.
openaire   +1 more source

Properties of High-Strength Concrete

Cement, Concrete, and Aggregates, 1986
Abstract This paper presents data related to the development of high-strength concrete with special emphasis on the development of high early strength. Both these objectives were achieved by using an ultrafine portland cement with a specific surface of about 750 m2/kg or a high early strength portland cement with about 75% tricalcium ...
openaire   +1 more source

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