Results 41 to 50 of about 17,164,985 (308)

Design of Heat Exchangers with Low-Boiling Working Fluids: Algorithm Development and Parameter Optimization

open access: yesEnergies
Heat exchangers are key components of advanced waste-heat recovery energy systems that operate on low-boiling working fluids. The efficiency and cost of power plants depend directly on their design characteristics.
Daniil Patorkin   +4 more
doaj   +1 more source

Path Optimization of Technological Innovation Efficiency Improvement in China’s High-Tech Industries Based on QCA and GA-PSO-BP Neural Network

open access: yesSystems, 2023
Innovation is the main driving force to promote national technological progress. It is of great significance to explore the optimal path to improve innovation efficiency by using the qualitative method and neural network prediction model to promote the ...
Yuanyuan Kou   +4 more
doaj   +1 more source

Research on the Framework of High-Tech Terrace Based on High-Tech Industry

open access: yesAdvances in Intelligent Systems Research, 2014
* National science and technology support project(2012BAH25F01) Abstract Nowadays, the High-Tech develop rapidly, the industrial clusters have been the important carrier to the economic development in our country, as well as the integrated form of science and technology service has been the objective needs to Chinese characteristic industry clusters ...
Tao Wang, Jiayi Yao, Jie Chen
openaire   +2 more sources

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Patent Signals of IPO Performance: Evidence from High- and Low-Tech Industries in Japan

open access: yesAsian Journal of Technology Management, 2022
Prior studies pointed to evidence that startups and venture capital (VC) companies tended to use different measures to provide signals to outsiders. This study adds to those previous insights by focusing on established firms’ patenting behaviors and ...
Le Thuy Ngoc An   +3 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Design and Simulation of a 3-MW L-Band Magnetron for Vehicle Stop System

open access: yesIEEE Access
This paper presents a design and simulation of a 3-MW-class L-band magnetron. The magnetron has 12 hole-and-slot resonators with double-strapped wires to eliminate the mode change during operation.
Hai Quan Ho   +7 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

High-tech industries in China and Russia: present situation and impact on economic development [PDF]

open access: yes, 2021
The competition of major countries in the world is mainly the competition of technological innovation, and technological innovation is manifested through high technology.
Wang, Yuchan, Wang Yuchan
core   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

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