Results 51 to 60 of about 1,688,919 (301)
Rab8a and Rab8b are essential for several apical transport pathways but insufficient for ciliogenesis [PDF]
, 2013 The small GTP-binding protein Rab8 is known to play an essential role in intracellular transport and cilia formation. We have previously demonstrated that Rab8a is required for localising apical markers in various organisms.
A. Harada +10 more
core +2 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
, 2008 Der Fokus staatlicher Forschungs- und Innovationspolitik richtet sich traditionell auf Spitzentechnologien. Die Prämisse dieser Politik ist, dass sich im Zeitalter der Globalisierung und der sich verschärfenden Innovationskonkurrenz das hiesige ...
Hirsch-Kreinsen, Hartmut
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Development of a control system for multiple unmanned aerial vehicles
International Journal of Advanced StudiesBackground. The study considers the problem associated with the development of a control system for many unmanned aerial vehicles. An analysis of the possibilities of improving the efficiency of control of unmanned aerial vehicle systems is carried out ...
Andrey P. Preobrazhenskiy +2 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Valuing high technology growth firms [PDF]
Journal of Business Economics, 2010 For the valuation of fast growing innovative firms Schwartz/Moon (2000, 2001) develop a fundamental valuation model where key parameters follow stochastic processes. While prior research shows promising potential for this model, it has never been tested on a large scale dataset. Thus, guided by economic theory, this paper is the first to design a large-
Soenke Sievers, Jan Klobucnik
openaire +1 more source
Novel Ruthenium-Silver PTA-Based Polymers and Their Behavior in Water [PDF]
, 2019 New coordination polymers based on two metal-containing moieties Ru–Ag are synthesized: Na[RuCpX(PTA)-μ-(PTA)-1κP:2κ2N-AgX2]∞ (X = Cl (1), Br (2), I (3)).
Fernández Barbero, Antonio José +4 more
core +1 more source
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source