Results 121 to 130 of about 18,606,918 (240)

Acidogenic fermentation of pretreated food waste under psychrophilic conditions for volatile fatty acids production

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract Mixed‐culture fermentation generally produces volatile fatty acids (VFAs) as a mixture of C2–C6 acids. Among operational parameters, temperature has a distinct effect on the microorganisms' metabolic activity, which can shift the composition of the metabolites.
Reema Kumar   +4 more
wiley   +1 more source

Bioeconomy, sustainability, and digital technologies in Haematococcus lacustris biomass and astaxanthin production: advances and outlook

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract Astaxanthin is a carotenoid with strong antioxidant properties, used in research on cancer treatment, ocular injuries, and neurological disorders. When produced by the microalgae Haematococcus lacustris, its antioxidant potential is even higher than that of the synthetic molecule, making it particularly attractive for pharmaceutical and ...
Renata Kühl Rocha   +5 more
wiley   +1 more source

Comparative Analysis of Bioreactor Design and Scale‐Up for Cultivated Meat Using Monte Carlo‐Based Timescale Modeling

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Cultivated meat offers a sustainable alternative to conventional livestock production but faces significant scale‐up challenges, particularly in bioreactor design for mammalian cell suspension cultures. This study presents a comparative analysis of stirred tank reactors (STR), bubble columns (BC), and airlift reactors (ALR) to assess their ...
Pieter Jan Theodoor Brorens   +2 more
wiley   +1 more source

High Cell Density Cultivation of HEK293 Cells Using a 2L Membrane‐Stirred Bioreactor

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The use of perfusion systems for the continuous cultivation of animal cells at high cell density (HCD) for the production of recombinant proteins, viruses, and viral vectors has many advantages. Besides an enhancement of volumetric productivity and high cell viability, the product quality can be improved through a steady‐state environment ...
Lennart Jacobtorweihe   +5 more
wiley   +1 more source

Scalable Separation and Purification of M13‐Bacteriophage‐Derived Particles Containing Artificial Single‐Stranded DNA Produced by Escherichia coli

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Single‐stranded DNA (ssDNA) solutions are promising innovations shaping the future of genetic research and medical therapies. In principle, biotechnological mass production of ssDNA can be achieved using Escherichia coli in a high‐cell density fed‐batch process by secreting phagemid particles derived from the filamentous M13 bacteriophages ...
Nathalie Hafner   +4 more
wiley   +1 more source

A General Workflow for Tangential Flow Filtration Perfusion Scale‐Up

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Tangential flow filtration (TFF) perfusion using hollow‐fiber modules offers substantial advantages over other mammalian cell retention technologies. Recently, increased awareness of Starling flow has helped to enhance filtration performance to similar, or even higher levels compared to alternative technologies.
Patrick Romann   +20 more
wiley   +1 more source

Reducing Cooling Costs for Sustainable Food Biomanufacturing With Thermotolerant Cupriavidus necator H16 Mutant

open access: yesBiotechnology and Bioengineering, EarlyView.
With a thermotolerant C. necator mutant the SCP production costs can be decreased by $0.98/kg. ABSTRACT Autotrophic CO2 conversion to Single Cell Protein (SCP) using H2 and O2 is gaining commercial traction for food and feed production. Cupriavidus necator H16 is a key chassis organism for this “knallgas” fermentation, but industrial operation is ...
Lars Puiman   +2 more
wiley   +1 more source

Scalable catalyst production process for oleate hydratase whole‐cell biocatalysis

open access: yesBiotechnology Progress, EarlyView.
This study establishes a scalable lactose‐induced fed‐batch fermentation for an Escherichia coli whole‐cell biocatalyst containing an oleate hydratase. Operation at a higher growth rate markedly increased biomass yields while maintaining catalyst activity and was demonstrated at 150 L scale.
Rebekka Horstmann   +6 more
wiley   +1 more source

Carbon Coking‐Tolerant Perovskite Catalyst Nd0.9Mg0.1Fe0.4Ni0.6O3 for Efficient Methane Dry Reforming

open access: yesCarbon and Hydrogen, EarlyView.
A new perovskite‐type catalyst Nd0.9Mg0.1Fe0.4Ni0.6O3 was developed for methane dry reforming, which exhibited 93.1% CH4 and 94.7% CO2 conversion with 100 h stability run and excellent anti‐coking capability, benefited from in situ exsolved Fe‐Ni alloy nanoparticles. ABSTRACT Perovskite with high temperature stability and tunability is a very promising
Zhenjie Wang, Xingchao Dai, Xinjiang Cui
wiley   +1 more source

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