Results 41 to 50 of about 501,364 (265)

Improving the high-temperature oxidation resistance of CrN coating by gradient deposition considering internal stress effects

Nuclear Materials and Energy, 2023
In this study, two different CrN coatings were deposited on the surface of Zr-4 via a multi-arc ion-plating method using gradient and non-gradient deposition processes.
Chuiyi Meng, Jishen Jiang, Jiaojiao Ma, Tianhao Zhang, Weizheng Liu, Peng Xie, Hui Wang, Xianfeng Ma, Xiujie He   +8 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

High temperature oxidation of corrosion resistant alloys from machine learning

npj Materials Degradation, 2021
Parabolic rate constants, k p , were collected from published reports and calculated from corrosion product data (sample mass gain or corrosion product thickness) and tabulated for 75 alloys exposed to temperatures between ~800 and 2000 K (~500–1700 oC ...
Christopher D. Taylor, Brett M. Tossey
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Thermodynamic modeling of the Hf-Ta-O system for the design of oxidation resistant HfC-TaC ceramics

Open Ceramics
An improved understanding of the oxidation resistance of HfC-TaC ultra-high temperature ceramics (UHTCs) is developed through modeling of the phase equilibria in the Hf-Ta-O system and HfO2-Ta2O5 isoplethal section. CALculation of PHAse Diagrams (CALPHAD)
Rahim Zaman, Elizabeth J. Opila, Bi-Cheng Zhou   +2 more
doaj   +1 more source

Oxidation Induced Stresses in High-Temperature Oxidation of Steel: A Multiphase Field Study

Metals, 2020
Oxide growth and the induced stresses in the high-temperature oxidation of steel were studied by a multiphase field model. The model incorporates both chemical and elastic energy to capture the coupled oxide kinetics and generated stresses.
Alireza Toghraee, Mohsen Asle Zaeem
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Air-SAGD technology for super-heavy oil reservoirs

Petroleum Exploration and Development, 2019
The air oxidation of super-heavy oil at low temperature was studied in laboratory and its influences on oil viscosity, component and steam sweep efficiency before and after air-injection were analyzed.
Yongrong GAO, Erpeng GUO, Dehuang SHEN, Bojun WANG   +3 more
doaj   +1 more source