Results 121 to 130 of about 2,919 (160)

Large‐Scale Structural Dynamics in the Tail Fiber Modulate the Infective Transition of the T7 Bacteriophage

Small, EarlyView.
During host recognition, the fibers of T7 bacteriophages transition from a capsid bound state to an extended conformation, which requires some level of fiber flexibility. By using high‐speed atomic force microscopy, we show that the fibers have an internal molecular hinge and a torsionally compliant coiled‐coil region.
Luca Elizabet Kosik, Miklós Cervenak, Dominik Sziklai, Andrea Balogh‐Molnár, Negar Rahimi, Bence Fehér, Soma Yamamoto, Hiroki Konno, Noriyuki Kodera, Holger Flechsig, Romain Amyot, Heinz Amenitsch, Hedvig Tordai, Levente Herényi, Ana Cuervo, Miklós Kellermayer, Bálint Kiss   +16 more
wiley   +1 more source

Diving Deeper Into Mechanisms of Acrylamide‐Induced Toxicity: RNA Sequencing Reveals Transcriptomic Alteration and Retrotransposon Expression in Drosophila melanogaster

Environmental Toxicology, EarlyView.
ABSTRACT Given the inevitability of human and animal exposure to acrylamide, there is increasing concern regarding its potential health risks. While a number of molecular mechanisms have been proposed, the complexity of acrylamide toxicological pathways and interactions remains incompletely characterized.
Oluwabukola Mary Farodoye, Titilayomi Ayomide Otenaike, Daniela Moreira Mombach, Monica Medeiros Silva, Amos Olalekan Abolaji, Elgion Lucio Da Silva Loreto   +5 more
wiley   +1 more source

Liquid biopsy in genitourinary oncology: Current clinical applications and future prospects across prostate, bladder, and renal cancers

UroPrecision, EarlyView.
Abstract Liquid biopsy has emerged as a transformative approach in oncology, providing minimally invasive access to tumor‐derived biomarkers with applications across diagnosis, prognosis, therapeutic guidance, and disease monitoring. This literature review synthesizes evidence from 125 studies evaluating circulating tumor DNA, circulating tumor cells ...
Kirolos Eskandar
wiley   +1 more source

Deciphering diverse cell‐death patterns to predict the prognosis and potential therapy target of hepatocellular carcinoma patients

VIEW, EarlyView.
Abstract Ninety percent of all primary liver malignancies are hepatocellular carcinomas (HCC), making liver cancer the third most common cause of cancer‐associated mortality. Different patterns of programmed cell death (PCD) are crucial for the survival of tumors, and they might serve as a prognostic marker for HCC.
Lin Ding, Qian Li, Wenjing Yang, Te Liu, Tongtong Tian, Yu Liu, Chunyan Zhang, Baishen Pan, Beili Wang, Fan Wu, Wei Guo   +10 more
wiley   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

VIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe, Satish Rojekar, Amol Gholap, K. Navaneetha Pandiyaraj, Mukesh Patekar, Claudia Riccardi, R. R. Deshmukh, Tomáš Kovářík, Kalim Deshmukh   +8 more
wiley   +1 more source

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Abstract 278: Reduced HtrA2 Protein Levels in Mitochondria but Elevated Levels in Cytosol of Left Ventricular Myocardium of Dogs with Chronic Heart Failure

Circulation Research, 2019
Background: The high-temperature requirement serine peptidase 2 (HtrA2) is a pro-apoptotic mitochondrial serine protease involved in caspase-dependent as well as caspase-independent programmed cell death.
Ramesh C. Gupta, V. Singh-Gupta, H. Sabbah   +2 more
semanticscholar   +1 more source

Monitoring and Characterization of Milk Fouling on Stainless Steel Using a High-Pressure High-Temperature Quartz Crystal Microbalance with Dissipation.

Langmuir, 2022
Fouling at interfaces deteriorates the efficiency and hygiene of processes within numerous industrial sectors, including the oil and gas, biomedical device, and food industries.
Holly A. Huellemeier, N. M. Eren, Taylor D Payne, Zachary D. Schultz, D. Heldman   +4 more
semanticscholar   +1 more source

Synthesis, characterization of high-temperature properties and evaluation of REBa2Cu3O6+δ (RE = La, Nd and Y) as cathode for intermediate-temperature solid-oxide fuel cells

Acta Crystallographica Section A: Foundations and Advances, 2021
Intermediate Temperature Solid Oxide Fuel Cells (IT – SOFCs) have proven to be a promising alternative in terms of efficient energy conversion in an environmentally friendly way, in which electrical work, water and heat are obtained as a result of a ...
Joaquín Grassi, L. Suescun, M. Macías, A. Serquis   +3 more
semanticscholar   +1 more source

[A 57-year-old male case of high temperature requirement A serine peptidase 1 (HTRA1)-related cerebral small vessel disease with "Chocolate Chip Sign" on ‍susceptibility-weighted imaging].

Rinshō shinkeigaku Clinical neurology
We report herein a 57-year-old man who presented with recurrent cerebral infarctions in one year. His father had multiple stroke episodes starting in his late 50s.
K. Takasone, Katsuya Nakamura, Satoru Shinriki, A. Ueda, Mitsuharu Ueda, Yoshiki Sekijima   +5 more
semanticscholar   +1 more source

A CORC® cable insert solenoid: the first high-temperature superconducting insert magnet tested at currents exceeding 4 kA in 14 T background magnetic field

Superconductors Science and Technology, 2020
The results presented in this Letter describe the successful test of the first high-temperature superconducting multi-tesla insert solenoid tested at currents exceeding 4 kA while operating in a background magnetic field of a low-temperature ...
D. C. van der Laan, J. Weiss, U. Trociewitz, D. Abraimov, A. Francis, J. Gillman, D. Davis, Y. Kim, V. Griffin, G. Miller, H. Weijers, L. Cooley, D. Larbalestier, X. R. Wang   +13 more
semanticscholar   +1 more source