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Bioinformatics for High Throughput Sequencing
2012Preface.- Introduction.- Overview of Sequencing Technology Platforms.- Applications of High Throughput Sequencing.- Computational Infrastructure and Basic Data Analysis for High-Throughput Sequencing.- Base-Calling for Bioinformaticians.- De Novo Short Read Assembly.- Short Read Mapping.- DNA-Protein Interaction Analysis (ChIP-Seq).- Genome-wide ...
Ana M. Aransay +2 more
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DNA sequencing in high-throughput neuroanatomy
Journal of Chemical Neuroanatomy, 2019Mapping brain connectivity at single cell resolution is critical for understanding brain structure. For decades, such mapping has been principally approached with microscopy techniques, aiming to visualize neurons and their connections. However, these techniques are often very labor intensive and do not scale well to the complexity of mammalian brains.
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Viral Detection by High-Throughput Sequencing
2014We applied a high-throughput sequencing platform, Ion PGM, for viral detection in fecal samples from adult cows collected in Hokkaido, Japan. Random RT-PCR was performed to amplify RNA extracted from 0.25 ml of fecal specimens (N = 8), and more than 5 μg of cDNA was synthesized. Unbiased high-throughput sequencing using the 318 v2 semiconductor chip of
Katsuro Hagiwara +3 more
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Analysis of High-Throughput Sequencing Data
2010Next-generation sequencing has revolutionized biology by exponentially increasing sequencing output while dramatically lowering costs. High-throughput sequence data with shorter reads has opened up new applications such as whole genome resequencing, indel and SNP detection, transcriptome sequencing, etc.
Bruno W. S. Sobral +2 more
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Applications of Ultra-high-Throughput Sequencing
2009The genomics era has enabled scientists to more readily pose truly global questions regarding mutation, evolution, gene and genome structure, function, and regulation. Just as Sanger sequencing ushered in a paradigm shift that enabled the molecular basis of biological questions to be directly addressed, to an even greater degree, ultra-high-throughput ...
Todd C. Mockler +2 more
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2011
Advances in DNA sequencing methods have a major impact on several biological fields, with microbiology being the first field to experience the benefits of knowing the exact sequence of a genome. This advantage held by the microbiology field was a result of the more compact nature of many microbial genomes, the long-standing history of microbes as model
Parla, J. +2 more
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Advances in DNA sequencing methods have a major impact on several biological fields, with microbiology being the first field to experience the benefits of knowing the exact sequence of a genome. This advantage held by the microbiology field was a result of the more compact nature of many microbial genomes, the long-standing history of microbes as model
Parla, J. +2 more
openaire +2 more sources
High throughput DNA sequencing: The new sequencing revolution
Plant Science, 2010Improvements in technology have rapidly changed the field of DNA sequencing. These improvements are boosted by bio-medical research. Plant science has benefited from this breakthrough, and a number of plant genomes are now available, new biological questions can be approached and new breeding strategies can be designed.
Bin Han, Yue-Ie C. Hsing, Michel Delseny
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Promises and pitfalls of using high‐throughput sequencing for diet analysis
Molecular Ecology Resources, 2018The application of high‐throughput sequencing‐based approaches to DNA extracted from environmental samples such as gut contents and faeces has become a popular tool for studying dietary habits of animals.
Antton Alberdi +6 more
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Mapping Algorithms in High-Throughput Sequencing
2021The launch of high-throughput sequencing led to the production of billions of DNA fragments of several organisms from the vast array of the biological specimen in one run. Because of the significant rise in the sequences number, most of the analytical time that was earlier expended processing biological information is now devoted to identifying where ...
S. Sabarinathan +6 more
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High-throughput sequencing view on the magnitude of global fungal diversity
Fungal diversity, 2021P. Baldrian +3 more
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