Results 51 to 60 of about 89,376 (259)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Cyber-attack-induced equilibria of high-voltage direct-current power transmission systems

Autonomous Intelligent Systems
The electric power system is the largest man-made autonomous intelligent machine, which is of vital importance but vulnerable to cyber threats. This study investigates cyber-attack-induced equilibria, i.e., steady-state operation points, of two-terminal ...
Haonan Xu, Qinyu Wei, Kaiyu Li, Xiaoqin Liu, Yulong Ding, Dongliang Zheng, Kairui Feng, Yue Song, Jiazuo Hou   +8 more
doaj   +1 more source

Assessment and enhancement of transfer capability for large-scale renewable generation base transmitted by voltage source converter based high voltage direct current system

International Journal of Electrical Power & Energy Systems
Voltage source converter based high voltage direct current transmission is a key method for transmitting large-scale renewable energy generation. The transfer capability of large-scale renewable generation base transmitted by voltage source converter ...
Shiyuan Chen, Shunjiang Lin, Yuerong Yang, Kaiyun Jiang, Mingbo Liu   +4 more
doaj   +1 more source

Master‐slave control strategy of the cascaded multi‐terminal ultra‐high voltage direct current transmission system

IET Generation, Transmission & Distribution, 2023
In the case of dispersed load consumption, Ultra‐high Voltage Direct Current (UHVDC) system in cascaded connection mode can significantly reduce the cost by building DC lines between different ends, but the communication delay caused by it brings ...
Sihang He, Liangliang Hao, Chang Liu, Jinghan He, Zhengguang Chen   +4 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

UHVDC Transmission Fault Location Based on Residual Convolutional Neural Network

Journal of Harbin University of Science and Technology
A method based on residual convolutional neural network for high-voltage direct current transmission fault location is proposed to address the issue of excessive reliance on the attenuation constant of the transmission line in traditional ultra-high ...
LI Ji, ZHANG Xueyou, ZHANG Junjie, SHI Wen, RUAN Wei, DAI Jianfeng   +5 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source