Results 51 to 60 of about 291,792 (316)

High-Dimensional $L_2$Boosting: Rate of Convergence

open access: yesJ. Mach. Learn. Res., 2016
19 pages, 4 tables; AMS 2000 subject classifications: Primary 62J05, 62J07, 41A25; secondary 49M15 ...
Ye Luo, Martin Spindler, Jannis Kueck
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Two-stage grid-connected inverter topology with high frequency link transformer for solar PV systems

open access: yesEnergy Reports, 2023
This study introduces a new topology for a single-phase photovoltaic (PV) grid connection. This suggested topology comprises two cascaded stages linked by a high-frequency transformer. In the first stage, a new buck–boost inverter with one energy storage
Ahmed Rashwan   +4 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Reordering Transaction Execution to Boost High-Frequency Trading Applications

open access: yesData Science and Engineering, 2017
High-frequency trading (HFT) has always been welcomed because it benefits not only personal benefits but also the whole social welfare. While the recent advance of portfolio selection in HFT market enables to bring about more profit, it yields much ...
Ningnan Zhou   +4 more
doaj   +1 more source

12-Pulse Rectifier with Two DCM Boost-Type Half-Controlled Bridges for Variable- Input-Frequency Applications

open access: yesEletrônica de Potência, 2021
This paper presents the analysis of the integration of two three-phase half-controlled boost converters, operating in discontinuous conduction mode (DCM), to the auto-connected 12-pulse rectifier.
João Carlos Pelicer Junior   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

High-gain quadratic boost DC converter based on cld module

open access: yesDianzi Jishu Yingyong, 2018
In order to meet the demand of high-gain direct-current boost converter in the process of using new energy, a novel quadratic boost direct-current converter is proposed.
Zhao Xinkuan   +3 more
doaj   +1 more source

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