Results 81 to 90 of about 17,220,096 (291)

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Numerical Study and Optimization of Combustion and Emissions of Ammonia/Diesel Dual-Fuel Engines Under Heavy Load

open access: yesEnergies
Ammonia fuel is expected to emerge as an effective alternative to fossil fuels due to its zero-carbon nature, high-efficiency storage and transportation advantages, and extensive industrial manufacturing infrastructure.
Shikai Xing   +8 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

On the performance of markup language compression [PDF]

open access: yes
Data compression is used in our everyday life to improve computer interaction or simply for storage purposes. Lossless data compression refers to those techniques that are able to compress a file in such ways that the decompressed format is the replica ...
Kheirkhahzadeh, Antonio
core   +3 more sources

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

On-board Data Processing to Lower Bandwidth Requirements on an Infrared Astronomy Satellite: Case of Herschel-PACS Camera

open access: yesEURASIP Journal on Advances in Signal Processing, 2005
This paper presents a new data compression concept, “on-board processing,” for infrared astronomy, where space observatories have limited processing resources.
Christian Reimers   +4 more
doaj   +1 more source

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