Results 71 to 80 of about 218,481 (259)

Numerical Demonstration of the Enhanced 3.7 μm Dispersive Wave Generation in an Er-Doped Fluorotellurite Fiber

IEEE Photonics Journal
We investigate theoretically the enhanced 3.7 μm mid-infrared (MIR) dispersive waves (DWs) generation in Er-doped fluorotellurite fibers with two zero-dispersion wavelengths (ZDWs).
Guochuan Ren, Chuanfei Yao, Linjing Yang, Xuan Wang, Yunhao Zhu, Pingxue Li   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

High-efficiency mid-infrared wavelength conversion in silicon waveguides [PDF]

APL Photonics
High-efficiency wavelength conversion into the 2 μm region has been achieved through Raman enhanced four-wave mixing in a planar silicon waveguide. By aligning the FWM phase-matching conditions with the Raman gain bandwidth, a wavelength conversion ...
T. Chen, M. Huang, S. Sun, C. Stirling, C. Mitchell, M. Nedeljkovic, G. Z. Mashanovich, A. C. Peacock   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

50 MHz–10 GHz Low-Power Resistive Feedback Current-Reuse Mixer with Inductive Peaking for Cognitive Radio Receiver

The Scientific World Journal, 2014
A low-power wideband mixer is designed and implemented in 0.13 µm standard CMOS technology based on resistive feedback current-reuse (RFCR) configuration for the application of cognitive radio receiver.
Nandini Vitee, Harikrishnan Ramiah, Wei-Keat Chong, Gim-Heng Tan, Jeevan Kanesan, Ahmed Wasif Reza   +5 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Comparative analysis of various restructured Quadratic Boost DC-DC converter [PDF]

E3S Web of Conferences
In this article, five high gain topologies are derived by reconfiguring the conventional quadratic boost converter. This restructuring is carried out by integrating high gain cells and modifying the topology.
Navamani Jayachandran Divya, Kathirvel Boopathi, Anbazhagan Lavanya   +2 more
doaj   +1 more source