PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro +6 more
wiley +1 more source
Comparison between defects and micro-notches in multiaxial fatigue – The size effect and the gradient effect [PDF]
Lien vers la version éditeur: http://www.sciencedirect.com/science/article/pii/S0142112308002156This paper attempts to improve the understanding of the multiaxial high cycle fatigue response of micro sized stress concentrations or notches of different ...
MOREL, Franck, NADOT, Yves, MOREL, Anne
core +1 more source
ABSTRACT Background We aimed to identify the proportion of individuals with a confirmed diagnosis of childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE) who show a negative routine EEG (rEEG), and to determine the main factors associated with this finding.
Francesco Fortunato +7 more
wiley +1 more source
Low cycle fatigue life improvement of AISI 304 by initial and intermittent wire brush hammering [PDF]
The effects of hammering by wire brush as a method of improving low cycle fatigue life of highly ductile austenitic stainless steel AISI 304 have been investigated through an experimental study combining imposed strain fatigue tests and assessment of ...
KHLIFI, Ammar +4 more
core +1 more source
A study of the low-cycle fatigue failure of a galvanised steel lighting column [PDF]
This paper presents the results of a low-cycle fatigue test on a galvanised steel lighting column. The aim of the test was to simulate the behaviour of the column undergoing large amplitude resonant vibration caused by wind.
Alexander, L.A., Wood, J.
core +4 more sources
Associations of Rheumatoid Arthritis Disease Activity With Frailty Over Five Years of Follow‐up
Objective To evaluate whether rheumatoid arthritis (RA) disease activity is associated with frailty both in cross‐section and longitudinally. Methods Participants within the Veterans Affairs Rheumatoid Arthritis (VARA) registry enrolled from 2003 to 2022 were included.
Courtney N. Loecker +14 more
wiley +1 more source
Fatigue Characteristics of Selected Light Metal Alloys
The paper addresses results of fatigue testing of light metal alloys used in the automotive as well as aerospace and aviation industries, among others.
Cieśla M., Junak G., Marek A.
doaj +1 more source
Cumulative Damage in Very High/Low Cycle Combined Fatigue for TC21 Titanium Alloy
The effect of low cycle fatigue (LCF) predamage with no precracks on very high cycle fatigue (VHCF) properties, and crack initiation characteristics for TC21 titanium alloy, was investigated.
Baohua Nie +7 more
doaj +1 more source
The effect of quenching and defects size on the HCF behaviour of Boron steel [PDF]
This work investigates the effect of natural and artificial surface defects and quenching on the fatigue strength of a Boron steel (22MnB5). A vast experimental campaign has been undertaken to study the high cycle fatigue behaviour and more specifically ...
PESSARD, Etienne +4 more
core +1 more source

