Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Random subspace-based ensemble classifier for high-dimensional data Using SPARK. [PDF]
Bhimineni VC, Senapati R.
europepmc +1 more source
Identification of prognostic and predictive biomarkers in high-dimensional data with PPLasso. [PDF]
Zhu W, Lévy-Leduc C, Ternès N.
europepmc +1 more source
The xyz algorithm for fast interaction search in high-dimensional data [PDF]
Gian-Andrea Thanei +2 more
openalex +1 more source
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown +6 more
wiley +1 more source
Signpost Testing to Navigate the Parameter Space of the Gaussian Graphical Model With High-Dimensional Data. [PDF]
Ruan K +2 more
europepmc +1 more source
Distribution-free fault identification and anomaly detection in high-dimensional data
Mehmet Turkoz
openalex +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Asymmetric canonical correlation analysis of Riemannian and high-dimensional data. [PDF]
Buenfil J, Lila E.
europepmc +1 more source
An Ensemble Outlier Detection Method Based on Information Entropy-Weighted Subspaces for High-Dimensional Data. [PDF]
Li Z, Zhang L.
europepmc +1 more source

