Results 21 to 30 of about 1,528,518 (167)

Radioactive Iodine-125 in Tumor Therapy: Advances and Future Directions

Frontiers in Oncology, 2021
Radioactive iodine-125 (I-125) is the most widely used radioactive sealed source for interstitial permanent brachytherapy (BT). BT has the exceptional ability to deliver extremely high doses that external beam radiotherapy (EBRT) could never achieve ...
Shuhua Wei, Chunxiao Li, Mengyuan Li, Yan Xiong, Yuliang Jiang, Haitao Sun, Bin Qiu, Christopher J. Lin, Junjie Wang   +8 more
doaj   +1 more source

The influence of beam parameters on FLASH effect

Frontiers in Oncology
Ultra-high dose rate radiotherapy (FLASH-RT) is typically defined as an external beam radiotherapy that utilizes a dose rate of 40 Gy/s or higher, compared with conventional dose rate radiotherapy (≤0.1 Gy/s).
Binwei Lin, Binwei Lin, Huan Du, Huan Du, Xiaofei Hao, Xiaofei Hao, Yuwen Liang, Haonan Xu, Wenqiang Tang, Jie Li, Jie Li, Yu Zhang, Yu Zhang, Xiao Bo Du, Xiao Bo Du, Xiao Bo Du   +15 more
doaj   +1 more source

Oxygen Depletion and the Role of Cellular Antioxidants in FLASH Radiotherapy: Mechanistic Insights from Monte Carlo Radiation-Chemical Modeling

Antioxidants
FLASH radiotherapy is a novel irradiation modality that employs ultra-high mean dose rates exceeding 40–150 Gy/s, far surpassing the typical ~0.03 Gy/s used in conventional radiotherapy.
Israth Rabeya, Jintana Meesungnoen, Jean-Paul Jay-Gerin   +2 more
doaj   +1 more source

Fractionated high dose rate versus low dose rate cervix cancer regimens

The British Journal of Radiology, 1991
Dr Orton's comments are both interesting and pertinent. As the linear-quadratic (L-Q) model increases in complexity from its early two parameter version (α/β early, α/β late), it becomes correspondingly harder to tie down all the relevant parameters. In our model of GYN HDR late effects, which Dr Orton has refitted using further data from his survey ...
D. J. Brenner, E. J. Hall
openaire   +2 more sources

Monte Carlo study of radiation dose enhancement by gadolinium in megavoltage and high dose rate radiotherapy. [PDF]

PLoS ONE, 2014
MRI is often used in tumor localization for radiotherapy treatment planning, with gadolinium (Gd)-containing materials often introduced as a contrast agent. Motexafin gadolinium is a novel radiosensitizer currently being studied in clinical trials.
Daniel G Zhang, Vladimir Feygelman, Eduardo G Moros, Kujtim Latifi, Geoffrey G Zhang   +4 more
doaj   +1 more source

Laser driven FLASH radiobiology using a high dose and ultra high dose rate single pulse proton source

Scientific Reports
Laser-driven proton sources have long been developed with an eye on their potential for medical application to radiation therapy. These sources are compact, versatile, and show peculiar characteristics such as extreme instantaneous dose rates, short ...
A. Flacco, E. Bayart, L. Romagnani, M. Cavallone, L. De Marzi, C. Fouillade, C. Giaccaglia, S. Heinrich, I. Lamarre-Jouenne, J. Monzac, K. Parodi, A. Patriarca, T. Rösch, J. Schreiber, L. Tischendorf   +14 more
doaj   +1 more source

Brachytherapy for Early Oral Tongue Cancer: Low Dose Rate to High Dose Rate [PDF]

Journal of Radiation Research, 2003
To examine the compatibility of low dose rate (LDR) with high dose rate (HDR) brachytherapy, we reviewed 399 patients with early oral tongue cancer (T1-2N0M0) treated solely by brachytherapy at Osaka University Hospital between 1967 and 1999. For patients in the LDR group (n = 341), the treatment sources consisted of Ir-192 pin for 227 patients (1973 ...
Hideya, Yamazaki, Takehiro, Inoue, Ken, Yoshida, Yasuo, Yoshioka, Souhei, Furukawa, Naoya, Kakimoto, Kimishige, Shimizutani, Toshihiko, Inoue   +7 more
openaire   +2 more sources

High-dose-rate brachytherapy in the treatment of skin Kaposi sarcoma

Journal of Contemporary Brachytherapy, 2017
Purpose : The aim of the study is to review our experience in treatment of Kaposi sarcoma (KS) lesions with high-dose-rate (HDR) brachytherapy. Material and methods : We present five new KS lesions (three patients) that were treated in our hospital ...
María Ángeles González Ruiz, Juan Quirós Rivero, Julia Luisa Muñoz García, Joaquín José Cabrera Rodríguez, Yesika Ríos Kavadoy, María Francisca Ropero Carmona, Almudena Corbacho Campos, Fernando García Urra, María Cristina Cruz Muñoz, Amanda Ruiz Herrero, Pedro Almendral Manzano   +10 more
doaj   +1 more source

Definitive three-dimensional high-dose-rate brachytherapy for inoperable endometrial cancer

Journal of Contemporary Brachytherapy, 2017
Purpose : To report our experience on high-dose-rate brachytherapy (HDR-BT) in patients with stage I-III endometrial cancer unfit to surgery. Material and methods : Seventeen patients underwent HDR-BT as definitive treatment.
Lorena Draghini, Ernesto Maranzano, Michelina Casale, Fabio Trippa, Paola Anselmo, Fabio Arcidiacono, Stefania Fabiani, Marco Italiani, Luigia Chirico, Marco Muti   +9 more
doaj   +1 more source

Improving prostate brachytherapy outcomes through MRI-Assisted dominant lesion dose painting

BMC Urology
Background The aim of this study was to assess the feasibility of using magnetic resonance (MR) images to implement a dose painting (DP) approach in prostate high-dose-rate brachytherapy.
Faranak Rahmani, Mohammad Javad Tahmasebi Birgani, Fatemeh Mohammadian, Maryam Feli, Seyed Masoud Rezaeijo   +4 more
doaj   +1 more source