Results 141 to 150 of about 22,051,772 (250)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

High Dynamic Range Image Hallucination

, 2008
We introduce high dynamic range image hallucination for adding high dynamic range details to the over-exposed and under-exposed regions of a low dynamic range image.
Sumanta Pattanaik (editors, Kun Zhou, Baining Guo, Lvdi Wang, Jan Kautz, Li-yi Wei   +5 more
core  

Simultaneous quantitative detection of multiple low-frequency variants by high-dynamic-range capillary electrophoresis. [PDF]

Mol Ther Nucleic Acids
Hagiwara Y, Tamamura N, Sumida N, Ono Y, Takahashi K, Sun Y, Koyama K, Ohtaki Y, Okada T, Kawabata H, Maeda C, Mori M, Matsumoto C, Suzuki M, Chiba SI, Tanino M, Taniue K, Kato H, Yamazaki M, Mizukami Y.   +19 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

High dynamic range volume visualization

, 2005
HDR rendering Tone mapping Raw data HDR image (pseudo color encoded) Tone mapped image Figure 1: Pipeline of high dynamic range volume visualization. The input is a scalar volume with high precision and/or high resolution (e.g. 20483). The user defines a
Xiaoru Yuan, Baoquan Chen, David H. Porter, Minh X. Nguyen   +3 more
core  

High dynamic range shortwave infrared imaging of mice with an InGaAs camera. [PDF]

J Biomed Opt
Patel A, Zhong X, Moffett M, Sun Y, Dennis AM.   +4 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

High-Dynamic-Range Absorption Spectroscopy of Polymer Sheets and Slabs by Integrating Sphere Illumination and Detection. [PDF]

Sensors (Basel)
Martinez-Anton JC.
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source