Results 241 to 250 of about 1,236,863 (298)

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Multicenter Evaluation of Label-Free Quantification in Human Plasma: Benchmarking with a High Dynamic Range Multispecies Sample Set

Distler U, Yoo H, Kardell O, Hein D, Sielaff M, Leps C, Scherer M, Gomez-Zepeda D, von Toerne C, Merl-Pham J, Barth T, Tüshaus, Giesbertz P, Müller T, Kliewer G, Aljakouch K, Helm B, Unger H, Frey D, Helm D, Schwarzmüller L, Popp O, Qin D, Wudy S, Sinn L, Mergner J, Ludwig C, Imhof A, Küster B, Lichtenthaler S, Krijgsveld J, Klingmueller U, Mertins P, Coscia F, Ralser M, Muelleder M, Hauck S, Tenzer S.   +37 more
europepmc   +1 more source

High dynamic range imaging [PDF]

ACM SIGGRAPH 2004 Course Notes, 2004
Current display devices can display only a limited range of contrast and colors, which is one of the main reasons that most image acquisition, processing, and display techniques use no more than eight bits per color channel. This course outlines recent advances in high-dynamic-range imaging, from capture to display, that remove this restriction ...
Paul E. Debevec, Erik Reinhard, Greg Ward, Sumanta N. Pattanaik   +3 more
openaire   +4 more sources

High dynamic range image hallucination [PDF]

ACM SIGGRAPH 2007 sketches, 2007
An apparatus and method provide for providing an output image from an input image. The input image may contain at least one portion that does not display certain desired information of the image, such as texture information. The desired information may be obtained from a second portion of the input image and applied to the at least one portion that ...
Zhou, K, Guo, B, Shum, HY, Wei, LY, Wang, L   +4 more
openaire   +3 more sources

High Dynamic Range Volume Visualization [PDF]

VIS 05. IEEE Visualization, 2005., 2005
High resolution volumes require high precision compositing to preserve detailed structures. This is even more desirable for volumes with high dynamic range values. After the high precision intermediate image has been computed, simply rounding up pixel values to regular display scales loses the computed details.
Xiaoru Yuan, Minh X. Nguyen, Baoquan Chen, David H. Porter   +3 more
openaire   +2 more sources

High Dynamic Range Global Mosaic [PDF]

, 2006
This paper presents a global approach for constructing high dynamic range mosaic from multiple images with large exposure differences. By relating image intensities to scene radiances with a convenient distortion model, we robustly estimated registration parameters for the high dynamic range global mosaic (HDRGM), simultaneously estimating scene ...
Kim, DW, Hong, KS
openaire   +3 more sources

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Adaptive High Dynamic Range

2015 23nd Signal Processing and Communications Applications Conference (SIU), 2015
Investigating High Dynamic Range (HDR) approaches in the literature, a new and adaptive HDR model is developed in this study. HDR is processed based on images taken as a Low Dynamic Range (LDR) scheme that ranges between low exposure and high exposure values.
Musa Atas, Yahya Dogan
openaire   +2 more sources