Results 91 to 100 of about 20,125,779 (304)
A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz +9 morewiley +1 more sourceCirculating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong +6 morewiley +1 more sourceATLAS search for new phenomena in dijet mass and angular distributions using pp collisions at root s=7 TeV [PDF]
, 2012 ATLAS Collaboration Contributor: Paul Douglas Jackson of SLAC National Accelerator Laboratory, Stanford CA, United States of America. Nitesh Soni of School of Chemistry and Physics, University of Adelaide, Adelaide, Australia.ATLAS Collaboration, G. Khoriauli, Alessandria, F, S. O. Holmgren, Arce ATH, Smizanska, M, Rosendahl, Peter Lundgaard, Blair, R, Keung, J, Ask S., Strang, M, Hasegawa, S., G. Eigen, Aguilar-Saavedra, J. A., Carminati, L., Cantero, J., Hubaut, F., M. Mazur, E. Etzion, P. Hansson, Meyer, C., Dudarev, A., Oren, Y., Skottowe, H, Borissov, G., Sjursen, Therese B., F. Dinut, Hellman, S, Harper, D, Korn, A., Oliver García, Elena, Laplace, S., Y. Smirnov, Higón Rodríguez, Emilio, Kim, H., D. Chakraborty, Bona M., Cavalli Sforza, M, Kanzaki, J, Bloch I., Schaefer, D., J. M. Seixas, Bortfeldt, Jonathan, A. Talyshev, Norton, PR, T. Naumann, Pranko, A, Abdel Khalek S., Epp, B., Hawkings, R. J., Clark A., Jakoubek, T, Fernando, W, Ahlen, S. P., Chang, Philip, Froeschl, R., J. Keung, G. Nunes Hanninger, Battistin, Michele, Brooijmans G., Anders, Gabriel, Leney, K, Childers, John Taylor, Joshi, K. D., J. Tojo, Dameri, M., Cindro, Vladimir, Daya-Ishmukhametova, R, Butler J. M., M. Villa, Abreu, H, Huettmann, A, Pizio, C., Eldik, N., A. Tonoyan, W. J. Dearnaley, Jon-And, K., B. Caron, Bundock A. C., Castillo Gimenez, Victoria, Köneke, K., Tasevsky, M., Acharya B. S., Siragusa, G, Gregor, I. M., Salzburger, A., Rossi, LP, S. Kaneti, Hadley, DR, Vacek, V, Carlino, G., R. Kopeliansky, Torrence, E., Oliveira, M, Bogaerts, J, I. Gough Eschrich, Snyder, S, Kirk, J, Ziolkowski, M, P. Grenier, Korotkov, VA, Kourkoumelis, C., Oh, S. H., V. Dao, Dai, T., Burdin, Sergey, Lefebvre, M, T. Mueller, M. Uslenghi, Chen, Chunhui, Bernat, P., G. Alexandre, I. N. Aleksandrov, Engl, A, A. Juste Rozas, Asai S, Arnault, C., Becker, Anne Kathrin, Bortolotto, V, Kiryunin, A, Anh, TV, Genest, MH, M. Klein, Addy, Tetteh, Negri, G., Moreno Llácer, María, Valkar, S, D. M. Rebuzzi, T. Todorov, Caminada L. M., T. Sumida, Olszewski, A., Knue, A, M. Medinnis, L. Mijović, Harris, O, D. Turecek, Hughes, G., Abolins, Maris, Cheatham, S, Joram, C, Mashimo, T, M. H. Genest, P. Stavina, Smizanska, M., Hughes, EW, Nelson, T. K., Padilla Aranda, C., Kersten, S, Pérez García-Estañ, M. T., Capeans Garrido, Maria Del Mar, Weng, Z., Schaepe, S., Schovancova, J., Ask, Stefan, M. S. Weber, Amelung, Christoph, Reale, V, Sircar, A., Vassilakopoulos, V, Oliveira, Miguel Alfonso, Bruneliere, R, S. Menke, Darlea, G, M. Agustoni, Potter, C. T., Massol, N, Annovi, Alberto, Benoit M, Morello, G., Buttinger, William, L. Rumyantsev, Negri, A., Canelli F., Kawamoto, T, K. Tackmann, Castaneda Miranda, E, Schamberger, RD, Manfredini, A, J. E. García Navarro, Ji, W., Teng, P. K., Michal, S, R. Camacho Toro, Lombardo, VP, D. G. Charlton, Salihagic, D, Karnevskiy, M., Papadelis, Aras,, B. Budick, J. Zhu, Wiik-Fuchs, LAM, Liu, C., Bronner, J., J. B. Liu, J. Toth, González de la Hoz, Santiago, Ertel, E., Cornelissen, T, Schwierz, R., J. L. Pinfold, Vincter, M. G., Kim, SH, D’Orazio, A., Fedin, OL, Barr, A, Köpke, L., J. Griffiths, Nisati, A, Strong, J, M. F. Tripiana, Amor Dos Santos, SP, Deviveiros, P, M. Werner, Marx, M, Liu, D., V. B?scher, A. F. Saavedra, A. Ludwig, Åkesson, Torsten Paul Ake, Burckhart H., V. Vrba, P. T. Keener, Selbach, K, V. Andrei, M. Wright, A. Petridis, Orr, R, Carrillo Montoya GD, O. Le Dortz, Lellouch, D., G. Cataldi, Bini, C, Hedberg, V, D. A. Milstead, Alvarez Gonzalez B., Ferretti, C., Bobbink, Gerjan, Kobel, M, E. Pasqualucci, Bednyakov, V, Lubatti, H, A. Polini, Salvachua Ferrando, B. M., Puzo, P, Nozka, L, Yu, J, R. Veness, Da Cunha Sargedas De Sousa, Mario Jose, Lancon, E, Marroquim, F, Yu, D, Z. Zhang, Abdelalim, A. A., Liss, T, Johansson, K. E., Bogouch, Andrei, Ellis, N, Benslama, K., Poel, E., Ellis, K, Norberg, S, Kolanoski, H., zur Nedden, M., Baak, M, Kowalewski, R., Sjölin, J., Bates, RL, K. Iordanidou, Wells, P. S., Oreglia, M, Borisov, Anatoly, Parzefall, U, F. M. Newcomer, Hillier, S, T. Nattermann, Samset, BH, Woudstra, MJ, Huseynov, N, N. Benekos, Medinnis, M., Charlton, D. G., R. Bates, Sadrozinski, H, Andreazza, Attilio, Arnault C., Tamsett, MC, Zhou, Y., Pauly, T, V. Kral, J. Cummings, Lopes, Lourenco, Albrand, Solveig, Errede, S., Liu, H., F. Niedercorn, R. Ueno, Petrucci, F., Rijssenbeek, M., Kaci, M, Marchese, F., R. Ströhmer, Krumshteyn, Z, T. Kuhl, G. Romeo, Dwuznik, M., Shatalov, PB, Smirnova, O, Arguin, J-F., Doi, Y., Cooke, M., B. Vachon, Richter, R., Smirnova, L, S. Schmitt, Diehl, E, Olchevski, A. G., Oberlack, H, L. Serkin, Avolio, G, Beau T., Dolgoshein, B. A., Broggi F., M. Garcia-Sciveres, Castillo Gimenez, V., Juste Rozas, A, T. M. Liss, Nikolic-Audit, I, Weng, Z, Sw. Banerjee, M. C. N. Fiolhais, Milov, A, A. J. Lowe, R. Seuster, P. Loch, E. Piccaro, Buat, Q., Donadelli, M., Taylor, F. E., S. Monzani, Morales, MIP, Blair, RE, Donadelli, M, McFarlane, K. W., Ros, E., Argyropoulos, S, Ciocca, C., G. Bobbink, Lipeles, E., R. Bartoldus, Molfetas, A., Tripiana, M. F., Bhimji W, Epp, B, Rybar, M, H. M. Gray, Cantrill, R, Zobernig, G., Kroha, H, Coccaro, A., Gössling, C., Clark PJ, Tsiareshka, PV, Augsten, Kamil, Meroni, C, Tayalati, Y, Ciftci AK, Branchini P, Y. Bai, Lie, K, Davygora, Y., Kawamura, G, Solovyev, V., Cardarelli R., E. Sarkisyan-Grinbaum, S. Bentvelsen, B. Martin dit Latour, Davies, M, Pommès, K., Byszewski, M, Andeen T, Strang, M., Klemetti, M, Conde Muiño, P., Jamin, D. O., Davies, E, Keung, J., Blumenschein U, Ippolito, V., Lantzsch, K., Sbrizzi, A., Camacho Toro, Reina Coromoto, Gray, J. A., Kuwertz, Emma,, Buchholz P., Abdinov, Ovsat Bahram oglu, Fournier, D., G. Otero y Garzon, Straessner, A., Y. Makida, Tylmad, M., Fiorini, L., C. Bertella, M. G. Wilson, Dudarev, A, Busato E, Schroeder, C., L. Batkova, W. Bell, Bittner, B., A. Dudarev, E. Ertel, Lange, C, Chafaq, A., Lantzsch, K, Grivaz, J.-F., Capua, Marcella, Bartsch, Valeria, Francavilla, P., Battistin M, Gorini, B., Wiglesworth, C., I. Bloch, Bromberg C., Hansen, J. B., Ueda, I., P. Wienemann, R. Armadans, Kroha, H., Beddall, A, Tsiskaridze, V, Alhroob, M., Tsiskaridze, S, Balek P., S. Heisterkamp, Bell, William, Kurata, M, Ren, Z, Salek, D, P. Calfayan, Maettig, S, Zevi della Porta, G., G. Anders, Bianchini, L., Webster, JS, Aliev M., J. M. Izen, Fisher, M, Lobodzinska, E., H. G. Sander, Bartoldus, R., Bagnaia P, Lagouri, T, Maettig, P, Patricelli, S., Verducci, M., J. Ebke, Bordoni, Stefania, Goussiou, AG, P. A. Bruckman, Wielers, M., Odaka, S, Nikolic-Audit, I., Kononov, AI, D. C. O’Neil, Walsh, B, D. S. Popovic, Hansen, J. D., Barajas, C, S. Cole, de Jong, P., Vermeulen, J. C., H. Ji, E. Vilucchi, Schorlemmer, A. L. S., J. Lorenz, P. Vankov, A. Ruschke, A. Gibson, Mechnich, J., Baranov, S, J. R. Carter, Chislett, RT, Hadavand, H. K., Baranov S. P., Soukharev, A, S. Vallecorsa, Ciftci, R., M. T. Pérez García-Estañ, M. Raymond, Oliver Garcia, E., Angelidakis, S, X. S. Anduaga, C. Stanescu, Hajduk, Z, S. Mahmoud, Zhou, B., Schwemling, Ph., Alexandre, G, Aleksandrov IN, Tovey, DR, Burgess, T., Kado, M., Khubua, J., Spagnolo, S., Ikeno, M., M. Pohl, M. Ciubancan, Brendlinger, K, Bocchetta, S, Gagnon, P., F. Hahn, Klok, P, Nakahama, Y., Brooijmans, Gustaaf, J. Kroseberg, J. Labbe, H. Li, Rybar, M., Chen Y., P. J. Clark, Schumm, BA, Popeneciu, G. A., Aharrouche, M, G. Alexander, H. Ma, Bremer, J., Cowan, G, Gadfort, T, AbouZeid, O, Ekelof, T., Shupe, M, Kluth, S., Chen X., Cakir O., Sipica, V., Errede, D., P. Cirkovic, Steele, G., El Moursli, RC, Levinson, L. J., Calafiura P., Beloborodova O, Seidel, SC, Cattai, A., O’Neil, D. C., Piec, S. M., Biesiada J., Sartisohn, G., Hryn'ova, T, D’Auria, S., Brandt G., M. Schumacher, P. Federic, Ladygin, E., Rubinskiy, I., Fratina, S., Carrillo-Montoya, G. D., J. Meyer, Makovec, N, Lundberg, B, Kabana, S., L. A. Bella, J. Buchanan, Lundberg, J, Bruschi, M, Bona, Marcella, S. Allwood Spiers, A. M. Castaneda, Lundberg, O, Giorgi, F, Sauvage, G, Bednyakov, V. A., Gorini, E., Zhou, N., Poveda, J., Grosse-Knetter, J., Lundberg, Olof,, Frank, T, Azuelos, G, Cerutti, F, Schwegler, P, Petrolo, E., Cheplakov A., Murray, W. J., G. L. Darlea, R. Hauser, Bouhova-Thacker EV, Vladoiu, D, Hansen, J. R., Calvet, D., Blocker C., L. Fayard, Tóth, József, H. Schulz, Nanava, G, Slater, M., Curatolo, M., Djobava, T., G. Poulard, N. Amram, V. B. Vinogradov, Hassani, S, M. Morii, Teixeira Dias Castanheira, M., Cavalleri P., Hillert, S, Cavasinni V., Wingerter-Seez, I., Krieger, N, Rossi, E., P. Gerlach, Krieger, P, Boumediene D., D. Kar, B. Liberti, Childers, J, B. H. Smart, García García, Carmen, G. Lenzen, Taylor, FE, Keeler, R., Bawa, HS, F. Derue, M-A. Dufour, Maltezos, S., Brandt A., Chu, M. L., T. Djobava, Belotskiy K., Stelzer-Chilton, O., P. W. Phillips, Wong, WC, Potter, C. J., H. G. Wilkens, Simic, L, Bachacou H., Brelier B, Saleem, M., Anduaga XS, C. Schiavi, Dhullipudi, R., Stradling, AR, Kar, D., Panduro Vazquez, J. G., Subramania, H, T. Nunnemann, A. Salamon, B. M. M., Laporte, JF, S. Stern, Taylor, C., K. Bos, Kishimoto, T., Goddard, J. R., Mechtel, M, Henrot-Versille, S., Bardin, DY, Lehmacher, M., Ancu L. S., Nugent, IM, Kono, T, Cerrito L., Bunse M., M. Caprini, Juste Rozas, A., J. Rothberg, Buttinger, W., Mc Kee, S. P., T. Wenaus, St Denis, RD, Paramonov, A, Joffe, D, Farrell, S, P. K. Behera, Seliverstov, D. M., Gray, H, Ženiš, T., Ramos, JAM, Gray, J, F. Quinonez, Rosenbaum, G, Blocker C, Gillberg, D, B. K. Gjelsten, D. M. Gingrich, Banas, E., Losty, M. J., Tani, K., Zhu, J., Martin, TA, Bianchi, R. M., Esposito, B, J. Schaarschmidt, Milov, A., Roda Dos Santos, D., Beau T, Bacci, C, T. Nobe, T. Colombo, B. Guo, D. Rahm, Malecki, Pa., Grishkevich, Y. V., Tani, K, V. Martinez Outschoorn, Harris, OM, Zhu, H., Ciocca, C, H. van der Graaf, Wu, SL, Kortner, O., Einsweiler, K., Abramowicz, Halina, Venturi, M., Bell W. H., T. Kobayashi, Brandt O., Catastini, P, O. Simard, Mechnich, J, Prokoshin, F, C. P. Paleari, De Groot, N, Weigell, P, P. Behera, M. Aurousseau, Ciftci R., Burckhart, H., H. K. Hadavand, Prasad, S., A. Lucotte, A. Zibell, Plamondon, M, X. Wu, B. Alvarez Gonzalez, Royon, C, J. Ferencei, Vartapetian, A, Derkaoui, J. E., H. Okawa, Buckley, AG, Ohm, C. C., Uchida, K., R. Keeler, Basye A., S. B. Harpaz, Cantrill, R., A. M. Castaneda Hernandez, Abdallah J, P. Dervan, S. Chekulaev, Labarga, L., Blazek, T., Harkusha, S., Meoni, E., Koutsman, A, Harvey, A., P. Koevesarki, Gallop, BJ, Dube, S., D. Levin, P. Schacht, J. Arguin, Kitamura, T., Caloba, L, Kogan, L, Clarke, R. N., Tassi, E, Bertin A, Calderini G, Pasqualucci, E., Simoniello, R, Roe, S., C. Friedrich, H. Burckhart, Fiolhais, MCN, S. Panitkin, Tikhomirov, V, Salvatore, D., P. U. E. Onyisi, Mayes, JB, Garrido, M, B. Osculati, Vuillermet, R, Turra, R., M. S. Neubauer, Oda, S, Cogan, JG, Randrianarivony, K., Caminada, Lea Michaela, Klimentov, A., M. Baker, Cowden, C, Brock I., Pagan Griso, S., S. Kabana, Del Peso, J, Rosenberg, EI, Scott, W. G., F. Conventi, Le Dortz, O, Y. Coadou, Kass, R, J. Ginzburg, R. Ciftci, Darbo, G., Protopopescu, S, A. Chitan, C. Haber, Kersevan, BP, R. Alon, Zhu, CG, D. Giugni, P. Vokac, Z. Zhao, Chen S., Antos, J, Rubinskiy, I, Kaczmarska, A, W. Brooks, Britton, Dave, Gorfine, G, Mandelli, L., Moore, R. W., van der Ster, D, Shao, Q. T., Alexa, C, Anulli F, Salvatore, F., S. Crépé-Renaudin, G. Negri, Sanchez Martinez, V., Barbaro Galtieri, A., Bogaerts, J. A., Bugge L., N. Davidson, Bortfeldt, J, Kuehn, S., H. Yang, Kantserov, VA, Kubota, T., Bhimji W., Schaile, D., Morettini, P, Nadal, J, Love, P. A., Bucci, F, T. J. Neep, P. Gutierrez, Potter, CJ, Harpaz, S, P. Laycock, K. Sliwa, R. D. St. Denis, Stroynowski, R, Thun, R. P., Romeo, G, J-Y. Hostachy, Torregrosa, E, Voss, R., Klinkby, E. B., Schaffer, AC, Cavasinni, Vincenzo, D'Auria, S, M. Shiyakova, Hance, M., Mitsui, S., Ko, B, Potter, CT, Yurkewicz, A, Teixeira-Dias, P, G. Alimonti, J. M. Butler, Chelstowska, M.A., Chen H., Sicho, P, M-L. Andrieux, Z. Czyczula, Bella, L. Aperio, Clarke, RN, Esch, H, Y. Tayalati, Chiefari, G, Capriotti D, K. Kroeninger, Christidi I. A., Papadelis, A, S. M. Consonni, J. Jia, Martin, JP, Krasznahorkay, Attila, Stanitzki, M, Karakostas, K, do Vale, M, Abjyan, T., S.w. Banerjee, Ciapetti G, von der Schmitt, H, Leontsinis, S., Boonekamp M, Addy TN, M. S. Alam, P. F. Giraud, E. Coniavitis, Anghinolfi F, Chu M. L., Aguilar Saavedra, J, Sosebee, M., C. Lapoire, Lenz, T., Lungwitz, M, Khalek, S, Petschull, D, C. P. Buszello, Huegging, F, Haug, S., Schwegler, Ph., Shimojima, M, Bozovic Jelisavcic I, Barreiro F, R. Mandrysch, M. Lassnig, Oakes, L. B., Reisinger, I, C. Petridou, P. Staroba, Voss, TT, Paleari, C, Abramowicz, H., Ilic, N, Raas, M., Yan, Z., Yasu, Y, A. Olariu, Meng, Z, Ishmukhametov, R., Tokushuku, K., Haywood, SJ, Moreno Llácer, M., Petridis, A., S. Kalinin, Terada, S., Cristinziani, M, A. Dafinca, Blondel, A., Le Guirriec, E., Head, SJ, Caron, S., Caputo R., Luijckx, G., Moeser, N, Maxfield, S. J., Smolek, K, K. Nagai, S. Tanaka, Barlow N, A. E. Barton, Y. S. Gao, E. Devetak, Wu, Y., Esposito, B., M. Ridel, Armbruster, A. J., Badescu, E, K. Ellis, J. A. Wilson, Albert, J., Chudoba, Jiri, K. Mönig, Chapman, J, Chekanov S., Huettmann, A., Wermes, N., Arik, M, Castaneda-Miranda, E, S. Pashapour, Wu, X., Washbrook, A, Koutsman, A., Matricon, P., C. Malone, Kortner, S., D. R. Quarrie, Yagci, KD, O. Bulekov, A. Coccaro, Ishino, M., D. Dobos, Scannicchio, DA, Borissov G., Arik, E, della Porta, GZ, G. Piacquadio, D. Berge, Torre, H., F. Prokoshin, E. Panagiotopoulou, Venturi, N., S. Hamilton +999 morecore +5 more sourcesRaman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans +3 morewiley +1 more sourceHigh-performance statistical methods for reactor neutrino oscillations
European Physical Journal C: Particles and FieldsWe present a PyTorch-based framework for forward folded reactor neutrino spectrum fitting that accelerates the two main bottlenecks: IBD mapping and detector response, using (i) result caching, (ii) banded sparse matrices, and (iii) blocked construction ...Jingqin Xue, Han Zhang, Hongfang Shen, Guangbao Sun, Dian Li, Liangqianjin Fan, Haifeng Yao, Liang Zhan, Xiang Zhou, Xuefeng Ding +9 moredoaj +1 more source
