Liposomal Nanoconfinement Enables Type I Photodynamic Conversion for Synergistic Cancer Photothermal-Immunotherapy. [PDF]
Liposomal nanoconfinement converts the hemicyanine photosensitizer RhM from Type‐II to Type‐I photodynamic therapy (PDT) while enhancing photothermal therapy (PTT). The RhM‐R837@Lip nanoassembly efficiently generates superoxide (O2•−) and hydroxyl radicals (•OH) to kill tumor cells and achieve tumor ablation.
Zhang M +14 more
europepmc +2 more sources
Strategic Design of Soft Actuators in Translational Medical Robotics for Human‐Centered Healthcare
Soft robotics enables biocompatible, compliant medical devices, but clinical translation requires design‐driven engineering beyond materials. This perspective reviews implantable, surgical, and wearable systems by actuation mechanism, highlighting how optimized architectures and integration improve mechanical interfacing, adaptability, and durability ...
Ho Jun Jin +3 more
wiley +1 more source
Learning to Classify from Impure Samples with High-Dimensional Data [PDF]
A persistent challenge in practical classification tasks is that labeled training sets are not always available. In particle physics, this challenge is surmounted by the use of simulations.
Komiske, Patrick T. +3 more
core +2 more sources
A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis
This study identifies the odd‐chain fatty acid C19:0 as an endogenous ligand of GPR120 that promotes glucose homeostasis via Gαq signaling. In obesity, elevated palmitic acid suppresses endogenous C19:0 production through a miRNA–PPARα–HACL1 pathway, offering a promising direction for understanding the role of OCFAs in human health.
Yanting Hou +14 more
wiley +1 more source
Minimum impact and immediacy of citations to physics open archives of arXiv.org: Science Citation Index based reports [PDF]
The present work has calculated the minimum Open Archive Impact Factors and Open Archive Immediacy Index for the Physics Classes of arXiv.org as calculated for traditional journals in Journal Citation Reports of the Institute of Scientific Information ...
Anil Kumar, * +4 more
core
In this course we will give examples for experimental techniques used in particle physics experiments. After a short introduction, we will discuss applications in silicon microstrip detectors, wire chambers, and single photon detection in Ring Imaging ...
Engelfried, J.
core +3 more sources
Deformation‐Induced Formation of Stray Grains in Additive Manufacturing of Single Crystals
Stray grain formation severely limits the additive manufacturing of single‐crystal alloys. By integrating in situ synchrotron techniques, ex situ characterization, and multi‐scale multi‐physics modeling, the authors reveal that stray grains originate from dislocations at the solid‐liquid interface, rather than thermal supercooling in conventional ...
Dongsheng Zhang +11 more
wiley +1 more source
Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan +8 more
wiley +1 more source
Review of the experimental evidence on pentaquarks and critical discussion
We review and discuss the experimental evidence on predicted baryonic states made by 4 quarks and one antiquark, called pentaquarks. Theoretical and experimental advances in the last few years led to the observation of pentaquark candidates by some ...
Kabana, Sonia
core +2 more sources
Extrahepatic Gene Editing In Vivo Using Organic Solvent‐Free Lipid Nanoparticles
This article highlights a novel, organic solvent‐free lipid nanoparticle (LNP) formulation that avoids cholesterol, thereby reducing hepatic accumulation and immune activation. These BLNPs enable potent, flexible, and scalable gene delivery, supporting personalized medicine and diverse nucleic acid applications.
Michael Streiber +14 more
wiley +1 more source

