Results 71 to 80 of about 404,474 (337)
Molecular Oncology, EarlyView.Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
Research Progress and Prospect of High-Entropy Alloy Materials
中国工程科学, 2023 With the rapid development of world’s technological level and the urgent demand of national economic construction for high-performance alloy materials, traditional single-component alloys gradually fail to satisfy the increasing service requirements ...
Li Tianxin +5 more
doaj +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Metals, 2021 High-performance structural materials are critical to the development of transportation, energy, and aerospace. In recent years, newly developed high-entropy alloys with a single-phase solid-solution structure have attracted wide attention from ...
Junqi Liu +5 more
doaj +1 more source
The effect of processing route on properties of HfNbTaTiZr high entropy alloy [PDF]
, 2019 High entropy alloys (HEA) have been one of the most attractive groups of materials for researchers in the last several years. Since HEAs are potential candidates for many (e.g., refractory, cryogenic, medical) applications, their properties are studied ...
Kim, Hyoung-Seop +8 more
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FEBS Open Bio, EarlyView.In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna +4 more
wiley +1 more source
The statistical physics of multi-component alloys using KKR-CPA
, 2015 We apply variational principles from statistical physics and the Landau theory of phase transitions to multicomponent alloys using the multiple-scattering theory of Korringa-Kohn-Rostoker (KKR) and the coherent potential approximation (CPA).
Khan, Suffian N. +2 more
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FEBS Open Bio, EarlyView.d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada +3 more
wiley +1 more source
Review on Preparation Technology and Properties of Refractory High Entropy Alloys
Materials, 2022 Refractory high entropy alloys have broad application prospects due to their excellent comprehensive properties in high temperature environments, and they have been widely implemented in many complex working conditions.
Xiqiang Ren +3 more
semanticscholar +1 more source
Structure and mechanical properties of Al-Co-Cr-Fe-Mn-Ni-Si-V high-entropy films obtained by splat-quenching [PDF]
, 2015 The multicomponent films of Al-Co-Cr-Fe-Mn-Ni-Si-V high-entropy alloys obtained by splat-quenching from melt were investigated. Phase formation criteria for high-entropy alloys were considered. The films have a structure with body-centered cubic lattice.
Bashev, V.F., Kushnerov, O.I.
core