Results 231 to 240 of about 19,637,528 (357)

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

Advanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao, Makiko Mori, Yuta Sekiguchi, Iori Morita, Ryota Shindoh, Shintaro Mandai, Tamami Fujiki, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Ayumi Suzuki, Yuji Nashimoto, Hirokazu Kaji, Yuma Waseda, Soichiro Yoshida, Yasuhisa Fujii, Eisei Sohara, Shinichi Uchida, Kensuke Miyake, Yutaro Mori   +20 more
wiley   +1 more source

Engineering of a high-fidelity Cas12a nuclease variant capable of allele-specific editing

Jingjing Wei, Jingtong Liu, Ziwen Wang, Yuan Yang, Yuwen Tian, Shengzhou Wang, Bao‐Qing Gao, Song Gao, Yang Li, Junnan Tang, Yongming Wang   +10 more
openalex   +2 more sources

Evaluating the Use of High-Fidelity Simulator Research Methods to Study Airline Flight Crew Resilience

, 2021
Chad L. Stephens, Lawrence J. Prinzel, Daniel Kiggins, Kathryn Ballard, Jon Holbrook   +4 more
openalex   +1 more source

Identification of determinants of high-fidelity DNA synthesis in Mycobacterium smegmatis DnaE1 through in silico and in vivo approaches. [PDF]

Nucleic Acids Res
Kuin RCM, van Westen GJP, Lamers MH.
europepmc   +1 more source

Geometrically Tunable Scaffold‐Free Muscle Bioconstructs for Treating Volumetric Muscle Loss

Advanced Healthcare Materials, EarlyView.
Volumetric muscle loss is associated with traumatic muscle resulting in permanent functional impairment. Mold‐based, scaffold‐free, high‐density muscle tissue bioconstructs are developed in customizable geometric shapes and sizes. The transplanted rectangular solid‐shaped muscle bioconstructs improved muscle force recovery and tissue regeneration in ...
Bugra Ayan, Gaoxian Chen, Ishita Jain, Sha Chen, Gladys Chiang, Caroline Hu, Renato Reyes, Beu P. Oropeza, Ngan F. Huang   +8 more
wiley   +1 more source

Validation of the Chinese version of the psychological safety in high-fidelity simulation scale: a culturally compatible methodological study. [PDF]

BMC Nurs
Li YY, Au ML, Tong LK, Fong IH, Ren XH, Cheng L.   +5 more
europepmc   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

Advanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu, Camilla Mussoni, Mateo S. Andrade Mier, Paula Buettner, Nathaly Chicaiza‐Cabezas, Yi‐Yu Robin Dai, Jessica Faber, Maren Fiedler, Zan Lamberger, Xuen Jen Ng, Vanessa Moessler, Anna Rederer, Jonas Roeder, Sabrina Stecher, Katinka Theis, Jeanette Weigelt, Silvia Budday, Gregor Lang, Natascha Schaefer   +18 more
wiley   +1 more source

Icecream: High-Fidelity Equivariant Cryo-Electron Tomography

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I.   +4 more
europepmc   +1 more source

CoreFormer high fidelity pulmonary nodule segmentation with structural core priors and geodesic implicit fields. [PDF]

NPJ Digit Med
Xi Y, Xu C, Ye F, Yuan M, Ye C, Jiang L, Huang Y, Zhang J, Liu M, Liu X, Yu B.   +10 more
europepmc   +1 more source