Results 81 to 90 of about 18,100,545 (183)

Clearance of p16‐positive cardiac cells improves age‐related cardiac remodeling in mice

Experimental Physiology, EarlyView.
Abstract Senescent cells are characterized by expression of markers like p16 and secretion of profibrotic and proinflammatory factors. The role of cellular senescence in age‐related cardiac remodeling and dysfunction is incompletely understood. This study aimed to: (i) evaluate the effect of p16‐ positive cell clearance on cardiac function and ...
Mozhdeh Mehdizadeh, Martin Mackasey, Kimia Gharagozloo, Martin Aguilar, Patrice Naud, Allan Ochs, Nhung Vuong‐Robillard, Eric Thorin, Gerardo Ferbeyre, Jean‐Claude Tardif, Martin G. Sirois, Jean Francois Tanguay, Stanley Nattel   +12 more
wiley   +1 more source

Electrophysiological properties of the dorsal motor nucleus of the vagus motoneurones controlling airway mucus secretion in rats

The Journal of Physiology, EarlyView.
Abstract figure legend Acidosis depolarises parasympathetic respiratory motoneurones in the dorsal motor nucleus of the vagus (DMV) and increases their firing frequency by reducing TWIK‐2 channel conductance. Acidosis also activates astrocytes, which further enhance neuronal excitability through NMDA receptor‐dependent glutamatergic signalling.
Daniel P. de Souza, Renato W. Martins Sá, Luiza Henrique de Souza, Fernando S. Ramalho, Davi J. A. Moraes   +4 more
wiley   +1 more source

Baseline characteristics of hospitalized patients with COVID-19 pneumonia receiving high flow nasal cannula treatment.

Baseline characteristics of hospitalized patients with COVID-19 pneumonia receiving high flow nasal cannula treatment.
Pitchayapa Ruchiwit (17972972), Jaturong Madua (17972975), Narongkorn Saiphoklang (5819789)   +2 more
core   +1 more source

Impact of High-Flow Nasal Cannula on Arterial Blood Gas Parameters in the Emergency Department

, 2020
Background: High-flow nasal cannula (HFNC) oxygen is becoming an integral part of respiratory failure management. Effects of HFNC on arterial blood gas (ABG) parameters especially partial carbon dioxide (PaCO2) require further investigation to provide ...
BAYRAM, BAŞAK, Sanci, Emre, Coskun, Feride Ercan, Basak Bayram, Emre Şancı, Feride Ercan Coşkun   +5 more
core   +1 more source

Comparison of the effectiveness of high-flow and conventional nasal cannula oxygen therapy in pulmonary embolism patients with acute hypoxemic respiratory failure.

, 2021
Introduction: The leading cause of mortality in pulmonary embolism (PE) is hypoxemic respiratory failure. The aim of this study was to compare the efficacy of high-flow nasal cannula (HFNC) and conventional nasal cannula (CNC) oxygen therapy in PE ...
Yılmazel Uçar, Elif, Aksakal, Alperen, Kerget, Buğra, Sağlam, Leyla   +3 more
core   +1 more source

The outcome of early use of high-velocity nasal insufflation in acute respiratory failure complicating coronavirus disease 2019

Egyptian Journal of Chest Disease and Tuberculosis
Background High-flow nasal cannula showed success in some coronavirus disease 2019 (COVID-19) patients. High-velocity nasal insufflation (Hi-VNI) is a refined form of high-flow nasal cannula that delivers heated and humidified gas with high velocity ...
Lamees M Bakkar, K Hussein, Samiaa H Sadek, Ebtsam S Abdulkareem   +3 more
doaj   +1 more source

Channelrhodopsin ion selectivity determines mechanisms and efficacy of optogenetic defibrillation in human atria and ventricles

The Journal of Physiology, EarlyView.
Abstract figure legend A, we used in silico models of human cardiomyocytes and microelectrode recordings on transgenic zebrafish hearts to study electrophysiology during optogenetic perturbations. Specifically, we compared effects of three distinct classes of channelrhodopsins: the cation non‐selective Chlamydomonas reinhardtii channelrhodopsin‐2 (ChR2)
Sophia Ohnemus, Albert Dasí, Ahmed F. Ramadan, Joachim Greiner, Eike M. Wülfers, Matthew R. Stoyek, Linda Tillert, Johannes Vierock, T. Alexander Quinn, Peter Kohl, Patrick M. Boyle, Viviane Timmermann, Franziska Schneider‐Warme   +12 more
wiley   +1 more source

Author's response to "High-flow nasal cannula therapy: an un-tapped resource"

, 2016
Author's response to "High-flow nasal cannula therapy: an un-tapped ...
GM Eastwood (14474697), N Fealy (13319268)   +1 more
core  

Effects of High Flow Nasal Cannula on breathing and the respiratory system parameters [PDF]

, 2019
Efekty vysokoprůtokové nosní kanyly (HFNC) na parametry ventilace a respirační soustavyEffects of High Flow Nasal Cannula on breathing and respiratory system ...
Jan Filip
core  

How to use humidified high-flow nasal cannula in breathless adults in the emergency department

, 2019
Undifferentiated breathlessness is a common presenting symptom in the ED.1 Until recently, supplemental oxygen via a facemask has been the ‘one‐size fits all’ initial treatment; however, research shows us that hyperoxaemia may be detrimental in some ...
Kylie Baker, John F Fraser, Greaves, T, Tanya Greaves, Baker, K, Fraser, JF, Greaves, Tanya, Baker, Kylie, Fraser, John F.   +8 more
core   +1 more source